EC number:2.4.1.15
| ID: | 2.4.1.15 |
|---|---|
| Description: | Alpha,alpha-trehalose-phosphate synthase (UDP-forming). |
| Alternative Name: |
UDP-glucose--glucose-phosphate glucosyltransferase. Trehalosephosphate-UDP glucosyltransferase. Trehalose phosphate synthetase. Trehalose phosphate synthase. Trehalose 6-phosphate synthetase. Trehalose 6-phosphate synthase. Transglucosylase. |
| Cath: | 3.40.50.20; 3.40.50.200; 3.40.50.2000; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.4.1.15 |
| BRENDA Enzyme Link: | BRENDA 2.4.1.15 |
| KEGG Enzyme Link: | KEGG2.4.1.15 |
| BioCyc Enzyme Link: | BioCyc 2.4.1.15 |
| ExPASy Enzyme Link: | ExPASy2.4.1.15 |
| EC2PDB Enzyme Link: | EC2PDB 2.4.1.15 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.4.1.15 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.4.1.15 |
| IntEnz Enzyme Link: | IntEnz 2.4.1.15 |
| MEDLINE Enzyme Link: | MEDLINE 2.4.1.15 |
| RHEA:18889 | D-glucose 6-phosphate + UDP-alpha-D-glucose = alpha,alpha-trehalose 6-phosphate + H(+) + UDP |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction |  |
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References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Biochemical and genetic characterization of osmoregulatory trehalose synthesis in Escherichia coli. | Giaever HM, Styrvold OB, Kaasen I, Strøm AR | 1988 Jun | 3131312 |
| Characterization of trehalose-6-phosphate synthase and trehalose-6-phosphate phosphatase of Saccharomyces cerevisiae. | Vandercammen A, François J, Hers HG | 1989 Jul 1 | 2546763 |
| The first prokaryotic trehalose synthase complex identified in the hyperthermophilic crenarchaeon Thermoproteus tenax. | Zaparty M, Hagemann A, Bräsen C, Hensel R, Lupas AN, Brinkmann H, Siebers B | 2013 | 23626675 |
| Mechanistic insight into enzymatic glycosyl transfer with retention of configuration through analysis of glycomimetic inhibitors. | Errey JC, Lee SS, Gibson RP, Martinez Fleites C, Barry CS, Jung PM, O'Sullivan AC, Davis BG, Davies GJ | 2010 Feb 8 | 20077550 |
| THE ENZYMES OF GLYCOGEN AND TREHALOSE SYNTHESIS IN SILK MOTH FAT BODY. | MURPHY TA, WYATT GR | 1965 Apr | 14285483 |
| PURIFICATION AND PROPERTIES OF THE TRANSGLUCOSYLASE INHIBITOR OF MYCOBACTERIUM TUBERCULOSIS. | LORNITZO FA, GOLDMAN DS | 1964 Sep | 14216421 |
| The biosynthesis of trehalose in the locust fat body. | CANDY DJ, KILBY BA | 1961 Mar | 13690400 |
| The biosynthesis of trehalose phosphate. | CABIB E, LELOIR LF | 1958 Mar | 13538966 |
| Trehalose-phosphate synthase of Mycobacterium tuberculosis. Cloning, expression and properties of the recombinant enzyme. | Pan YT, Carroll JD, Elbein AD | 2002 Dec | 12473104 |