EC number:2.4.1.150
| ID: | 2.4.1.150 |
|---|---|
| Description: | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase. |
| Alternative Name: |
N-acetylglucosaminyltransferase. I-branching beta-1,6-N-acetylglucosaminyltransferase. |
3D structure
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 2.4.1.150 |
| BRENDA Enzyme Link: | BRENDA 2.4.1.150 |
| KEGG Enzyme Link: | KEGG2.4.1.150 |
| BioCyc Enzyme Link: | BioCyc 2.4.1.150 |
| ExPASy Enzyme Link: | ExPASy2.4.1.150 |
| EC2PDB Enzyme Link: | EC2PDB 2.4.1.150 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.4.1.150 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.4.1.150 |
| IntEnz Enzyme Link: | IntEnz 2.4.1.150 |
| MEDLINE Enzyme Link: | MEDLINE 2.4.1.150 |
EC number:2.4.1.150
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:54820 | a beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + UDP-N-acetyl-alpha-D-glucosamine = a beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-[beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:6]-[O;H0;+0:7]-[CH;+0:3](-[*:4])-[*:5].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Genomic organization of core 2 and I branching beta-1,6-N-acetylglucosaminyltransferases. Implication for evolution of the beta-1,6-N-acetylglucosaminyltransferase gene family. | Bierhuizen MF, Maemura K, Kudo S, Fukuda M | 1995 Jun | 7579796 |
| Biosynthesis of blood group I antigens. Identification of a UDP-GlcNAc:GlcNAc beta 1-3Gal(-R) beta 1-6(GlcNAc to Gal) N-acetylglucosaminyltransferase in hog gastric mucosa. | Piller F, Cartron JP, Maranduba A, Veyrières A, Leroy Y, Fournet B | 1984 Nov 10 | 6490658 |
| Biosynthesis in vitro of Ii core glycosphingolipids from neolactotetraosylceramide by beta 1-3- and beta 1-6-N-acetylglucosaminyltransferases from mouse T-lymphoma. | Basu M, Basu S | 1984 Oct 25 | 6238026 |
| Regulation of I-branched poly-N-acetyllactosamine synthesis. Concerted actions by I-extension enzyme, I-branching enzyme, and beta1,4-galactosyltransferase I. | Ujita M, McAuliffe J, Suzuki M, Hindsgaul O, Clausen H, Fukuda MN, Fukuda M | 1999 Apr 2 | 10092606 |
| Molecular cloning and expression of a novel beta-1, 6-N-acetylglucosaminyltransferase that forms core 2, core 4, and I branches. | Yeh JC, Ong E, Fukuda M | 1999 Jan 29 | 9915862 |
| A multipotential beta -1,6-N-acetylglucosaminyl-transferase is encoded by bovine herpesvirus type 4. | Vanderplasschen A, Markine-Goriaynoff N, Lomonte P, Suzuki M, Hiraoka N, Yeh JC, Bureau F, Willems L, Thiry E, Fukuda M, Pastoret PP | 2000 May 23 | 10811884 |
| Novikoff ascites tumor cells contain N-acetyllactosaminide beta 1 leads to 3 and beta 1 leads to 6 N-acetylglucosaminyltransferase activity. | van den Eijnden DH, Winterwerp H, Smeeman P, Schiphorst WE | 1983 Mar 25 | 6219989 |
| RHEA:17413 | a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-beta-D-glucosaminyl-(1->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Molecular cloning and expression of a novel beta-1, 6-N-acetylglucosaminyltransferase that forms core 2, core 4, and I branches. | Yeh JC, Ong E, Fukuda M | 1999 Jan 29 | 9915862 |
| A multipotential beta -1,6-N-acetylglucosaminyl-transferase is encoded by bovine herpesvirus type 4. | Vanderplasschen A, Markine-Goriaynoff N, Lomonte P, Suzuki M, Hiraoka N, Yeh JC, Bureau F, Willems L, Thiry E, Fukuda M, Pastoret PP | 2000 May 23 | 10811884 |
| Novikoff ascites tumor cells contain N-acetyllactosaminide beta 1 leads to 3 and beta 1 leads to 6 N-acetylglucosaminyltransferase activity. | van den Eijnden DH, Winterwerp H, Smeeman P, Schiphorst WE | 1983 Mar 25 | 6219989 |