EC number:2.4.1.182

Enzyme

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EC Tree
     2. Transferases
        2.4 Glycosyltransferases
            2.4.1 Hexosyltransferases
ID:2.4.1.182
Description:Lipid-A-disaccharide synthase.
Cath: 1.20.1180.10; 2.160.10.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.1.182
BRENDA Enzyme Link: BRENDA 2.4.1.182
KEGG Enzyme Link: KEGG2.4.1.182
BioCyc Enzyme Link: BioCyc 2.4.1.182
ExPASy Enzyme Link: ExPASy2.4.1.182
EC2PDB Enzyme Link: EC2PDB 2.4.1.182
ExplorEnz Enzyme Link: ExplorEnz 2.4.1.182
PRIAM enzyme-specific profiles Link: PRIAM 2.4.1.182
IntEnz Enzyme Link: IntEnz 2.4.1.182
MEDLINE Enzyme Link: MEDLINE 2.4.1.182

EC number:2.4.1.182

MSA:

2.4.1.182;
Phylogenetic Tree:

2.4.1.182;
Uniprot:
M-CSA:
RHEA:22668 2-N,3-O-bis(3-hydroxytetradecanoyl)-alpha-D-glucosaminyl 1-phosphate + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine = H(+) + lipid A disaccharide (E. coli) + UDP
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:6]-[O;H0;+0:7]-[CH;+0:3](-[*:4])-[*:5].[*:1]-[OH;+0:2]
Reaction
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References

TitleAuthorsDatePubMed ID
The biosynthesis of gram-negative endotoxin. Formation of lipid A disaccharides from monosaccharide precursors in extracts of Escherichia coli.Ray BL, Painter G, Raetz CR1984 Apr 256370995
Nucleotide sequence of the Escherichia coli gene for lipid A disaccharide synthase.Crowell DN, Reznikoff WS, Raetz CR1987 Dec2824445