EC number:2.4.1.195
| ID: | 2.4.1.195 | ||
|---|---|---|---|
| Description: | N-hydroxythioamide S-beta-glucosyltransferase. | ||
| Alternative Name: |
Uridine diphosphoglucose-thiohydroximate glucosyltransferase. UGT74B1. Thiohydroximate S-glucosyltransferase. Thiohydroximate glucosyltransferase. Thiohydroximate beta-D-glucosyltransferase. Desulfoglucosinolate-uridine diphosphate glucosyltransferase. | ||
| Prosite: | PDOC00359; | ||
| PDB: |
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3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.4.1.195 |
| BRENDA Enzyme Link: | BRENDA 2.4.1.195 |
| KEGG Enzyme Link: | KEGG2.4.1.195 |
| BioCyc Enzyme Link: | BioCyc 2.4.1.195 |
| ExPASy Enzyme Link: | ExPASy2.4.1.195 |
| EC2PDB Enzyme Link: | EC2PDB 2.4.1.195 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.4.1.195 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.4.1.195 |
| IntEnz Enzyme Link: | IntEnz 2.4.1.195 |
| MEDLINE Enzyme Link: | MEDLINE 2.4.1.195 |
EC number:2.4.1.195
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:52152 | (E)-2-(1H-indol-3-yl)-1-thioacetohydroximate + UDP-alpha-D-glucose = indolylmethyl-desulfoglucosinolate + UDP |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[SH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[S;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Molecular cloning of a Brassica napus thiohydroximate S-glucosyltransferase gene and its expression in Escherichia coli. | Marillia EF, MacPherson JM, Tsang EW, Van Audenhove K, Keller WA, GrootWassink JW | 2001 Oct | 12060294 |
| A radioassay of enzymes catalyzing the glucosylation and sulfation steps of glucosinolate biosynthesis in Brassica species. | Jain JC, Reed DW, GrootWassink JW, Underhill EW | 1989 Apr | 2524977 |
| Purification and properties of UDP-glucose:thiohydroximate glucosyltransferase from Brassica napus L. seedlings. | Reed DW, Davin L, Jain JC, Deluca V, Nelson L, Underhill EW | 1993 Sep | 8373190 |
| Arabidopsis glucosyltransferase UGT74B1 functions in glucosinolate biosynthesis and auxin homeostasis. | Grubb CD, Zipp BJ, Ludwig-Müller J, Masuno MN, Molinski TF, Abel S | 2004 Dec | 15584955 |
| The chemical diversity and distribution of glucosinolates and isothiocyanates among plants. | Fahey JW, Zalcmann AT, Talalay P | 2001 Jan | 11198818 |
| RHEA:52148 | an (E)-omega-(methylsulfanyl)alkyl-thiohydroximate + UDP-alpha-D-glucose = an aliphatic desulfo-glucosinolate + UDP |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[SH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[S;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Molecular cloning of a Brassica napus thiohydroximate S-glucosyltransferase gene and its expression in Escherichia coli. | Marillia EF, MacPherson JM, Tsang EW, Van Audenhove K, Keller WA, GrootWassink JW | 2001 Oct | 12060294 |
| A radioassay of enzymes catalyzing the glucosylation and sulfation steps of glucosinolate biosynthesis in Brassica species. | Jain JC, Reed DW, GrootWassink JW, Underhill EW | 1989 Apr | 2524977 |
| Purification and properties of UDP-glucose:thiohydroximate glucosyltransferase from Brassica napus L. seedlings. | Reed DW, Davin L, Jain JC, Deluca V, Nelson L, Underhill EW | 1993 Sep | 8373190 |
| Arabidopsis glucosyltransferase UGT74B1 functions in glucosinolate biosynthesis and auxin homeostasis. | Grubb CD, Zipp BJ, Ludwig-Müller J, Masuno MN, Molinski TF, Abel S | 2004 Dec | 15584955 |
| The chemical diversity and distribution of glucosinolates and isothiocyanates among plants. | Fahey JW, Zalcmann AT, Talalay P | 2001 Jan | 11198818 |
| RHEA:13757 | (Z)-2-phenyl-1-thioacetohydroximate + UDP-alpha-D-glucose = (Z)-desulfoglucotropeolin + UDP |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[SH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[S;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and properties of UDP-glucose:thiohydroximate glucosyltransferase from Brassica napus L. seedlings. | Reed DW, Davin L, Jain JC, Deluca V, Nelson L, Underhill EW | 1993 Sep | 8373190 |
| Arabidopsis glucosyltransferase UGT74B1 functions in glucosinolate biosynthesis and auxin homeostasis. | Grubb CD, Zipp BJ, Ludwig-Müller J, Masuno MN, Molinski TF, Abel S | 2004 Dec | 15584955 |
| The chemical diversity and distribution of glucosinolates and isothiocyanates among plants. | Fahey JW, Zalcmann AT, Talalay P | 2001 Jan | 11198818 |