EC number:2.4.1.206

Enzyme

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EC Tree
     2. Transferases
        2.4 Glycosyltransferases
            2.4.1 Hexosyltransferases
ID:2.4.1.206
Description:Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.1.206
BRENDA Enzyme Link: BRENDA 2.4.1.206
KEGG Enzyme Link: KEGG2.4.1.206
BioCyc Enzyme Link: BioCyc 2.4.1.206
ExPASy Enzyme Link: ExPASy2.4.1.206
EC2PDB Enzyme Link: EC2PDB 2.4.1.206
ExplorEnz Enzyme Link: ExplorEnz 2.4.1.206
PRIAM enzyme-specific profiles Link: PRIAM 2.4.1.206
IntEnz Enzyme Link: IntEnz 2.4.1.206
MEDLINE Enzyme Link: MEDLINE 2.4.1.206

EC number:2.4.1.206

MSA:

2.4.1.206;
Phylogenetic Tree:

2.4.1.206;
Uniprot:
M-CSA:
RHEA:13905 beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine = beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-N-acylsphing-4-enine + H(+) + UDP
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:6]-[O;H0;+0:7]-[CH;+0:3](-[*:4])-[*:5].[*:1]-[OH;+0:2]
Reaction
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References

TitleAuthorsDatePubMed ID
Glycosphingolipid glycosyltransferases in human fetal brain.Percy AK, Gottfries J, Vilbergsson G, Månsson JE, Svennerholm L1991 May1901591
Glycolipids and glycosyltransferases in permanent cell lines established from human medulloblastomas.Gottfries J, Percy AK, Månsson JE, Fredman P, Wikstrand CJ, Friedman HS, Bigner DD, Svennerholm L1991 Feb 51825612
Cloning of a mouse beta 1,3 N-acetylglucosaminyltransferase GlcNAc(beta 1,3)Gal(beta 1,4)Glc-ceramide synthase gene encoding the key regulator of lacto-series glycolipid biosynthesis.Henion TR, Zhou D, Wolfer DP, Jungalwala FB, Hennet T2001 Aug 1011384981
Molecular cloning and characterization of UDP-GlcNAc:lactosylceramide beta 1,3-N-acetylglucosaminyltransferase (beta 3Gn-T5), an essential enzyme for the expression of HNK-1 and Lewis X epitopes on glycolipids.Togayachi A, Akashima T, Ookubo R, Kudo T, Nishihara S, Iwasaki H, Natsume A, Mio H, Inokuchi J, Irimura T, Sasaki K, Narimatsu H2001 Jun 2211283017