EC number:2.4.1.22
| ID: | 2.4.1.22 |
|---|---|
| Description: | Lactose synthase. |
| Alternative Name: |
UDP-galactose--glucose galactosyltransferase. N-acetyllactosamine synthase. |
| Cath: | 3.90.550.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.4.1.22 |
| BRENDA Enzyme Link: | BRENDA 2.4.1.22 |
| KEGG Enzyme Link: | KEGG2.4.1.22 |
| BioCyc Enzyme Link: | BioCyc 2.4.1.22 |
| ExPASy Enzyme Link: | ExPASy2.4.1.22 |
| EC2PDB Enzyme Link: | EC2PDB 2.4.1.22 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.4.1.22 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.4.1.22 |
| IntEnz Enzyme Link: | IntEnz 2.4.1.22 |
| MEDLINE Enzyme Link: | MEDLINE 2.4.1.22 |
| RHEA:12404 | D-glucose + UDP-alpha-D-galactose = H(+) + lactose + UDP |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3]1-[*:4]-[*:5]-[CH;+0:6](-[OH;+0:7])-[*:8]-[*:9]-1.[*:10]-[OH;+0:11]>>[*:10]-[O;H0;+0:11]-[CH;+0:6]1-[*:5]-[*:4]-[CH;+0:3](-[OH;+0:7])-[*:9]-[*:8]-1.[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Lactose synthetase. | Hill RL, Brew K | 1975 | 812340 |
| Alpha-lactalbumin and the lactose synthetase reaction. | Fitzgerald DK, Brodbeck U, Kiyosawa I, Mawal R, Colvin B, Ebner KE | 1970 Apr 25 | 5440844 |
| High-throughput mass-spectrometry monitoring for multisubstrate enzymes: determining the kinetic parameters and catalytic activities of glycosyltransferases. | Yang M, Brazier M, Edwards R, Davis BG | 2005 Feb | 15678424 |
| The synthesis of lactose by particulate enzyme preparations from guinea pig and bovine mammary glands. | WATKINS WM, HASSID WZ | 1962 May | 14005251 |