Enzyme

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     2. Transferases
        2.4 Glycosyltransferases
            2.4.1 Hexosyltransferases
ID:2.4.1.245
Description:Alpha,alpha-trehalose synthase.
Alternative Name: Trehalose synthetase.
Trehalose synthase.
Cath: 3.40.50.20; 3.40.50.200; 3.40.50.2000;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.1.245
BRENDA Enzyme Link: BRENDA 2.4.1.245
KEGG Enzyme Link: KEGG2.4.1.245
BioCyc Enzyme Link: BioCyc 2.4.1.245
ExPASy Enzyme Link: ExPASy2.4.1.245
EC2PDB Enzyme Link: EC2PDB 2.4.1.245
ExplorEnz Enzyme Link: ExplorEnz 2.4.1.245
PRIAM enzyme-specific profiles Link: PRIAM 2.4.1.245
IntEnz Enzyme Link: IntEnz 2.4.1.245
MEDLINE Enzyme Link: MEDLINE 2.4.1.245
MSA:

2.4.1.245;

Phylogenetic Tree:

2.4.1.245;

Uniprot:
M-CSA:
RHEA:47416 an NDP-alpha-D-glucose + D-glucose = a ribonucleoside 5'-diphosphate + alpha,alpha-trehalose + H(+)
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2]
Reaction
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References

TitleAuthorsDatePubMed ID
Structural insights on the new mechanism of trehalose synthesis by trehalose synthase TreT from Pyrococcus horikoshii.Woo EJ, Ryu SI, Song HN, Jung TY, Yeon SM, Lee HA, Park BC, Park KH, Lee SB2010 Nov 2620888836
A unique combination of genetic systems for the synthesis of trehalose in Rubrobacter xylanophilus: properties of a rare actinobacterial TreT.Nobre A, Alarico S, Fernandes C, Empadinhas N, da Costa MS2008 Dec18835983
A novel trehalose synthesizing pathway in the hyperthermophilic Crenarchaeon Thermoproteus tenax: the unidirectional TreT pathway.Kouril T, Zaparty M, Marrero J, Brinkmann H, Siebers B2008 Sep18483808
A novel trehalose-synthesizing glycosyltransferase from Pyrococcus horikoshii: molecular cloning and characterization.Ryu SI, Park CS, Cha J, Woo EJ, Lee SB2005 Apr 815737605
TreT, a novel trehalose glycosyltransferring synthase of the hyperthermophilic archaeon Thermococcus litoralis.Qu Q, Lee SJ, Boos W2004 Nov 1215364950

RHEA:25408 ADP-alpha-D-glucose + D-glucose = ADP + alpha,alpha-trehalose + H(+)
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2]
Reaction
Core-to-Core More
Core-to-Core More
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