| ID: | 2.4.1.245 |
|---|---|
| Description: | Alpha,alpha-trehalose synthase. |
| Alternative Name: |
Trehalose synthetase. Trehalose synthase. |
| Cath: | 3.40.50.20; 3.40.50.200; 3.40.50.2000; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 2.4.1.245 |
| BRENDA Enzyme Link: | BRENDA 2.4.1.245 |
| KEGG Enzyme Link: | KEGG2.4.1.245 |
| BioCyc Enzyme Link: | BioCyc 2.4.1.245 |
| ExPASy Enzyme Link: | ExPASy2.4.1.245 |
| EC2PDB Enzyme Link: | EC2PDB 2.4.1.245 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.4.1.245 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.4.1.245 |
| IntEnz Enzyme Link: | IntEnz 2.4.1.245 |
| MEDLINE Enzyme Link: | MEDLINE 2.4.1.245 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:47416 | an NDP-alpha-D-glucose + D-glucose = a ribonucleoside 5'-diphosphate + alpha,alpha-trehalose + H(+) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction | ![]() |
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| Core-to-Core | |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Structural insights on the new mechanism of trehalose synthesis by trehalose synthase TreT from Pyrococcus horikoshii. | Woo EJ, Ryu SI, Song HN, Jung TY, Yeon SM, Lee HA, Park BC, Park KH, Lee SB | 2010 Nov 26 | 20888836 |
| A unique combination of genetic systems for the synthesis of trehalose in Rubrobacter xylanophilus: properties of a rare actinobacterial TreT. | Nobre A, Alarico S, Fernandes C, Empadinhas N, da Costa MS | 2008 Dec | 18835983 |
| A novel trehalose synthesizing pathway in the hyperthermophilic Crenarchaeon Thermoproteus tenax: the unidirectional TreT pathway. | Kouril T, Zaparty M, Marrero J, Brinkmann H, Siebers B | 2008 Sep | 18483808 |
| A novel trehalose-synthesizing glycosyltransferase from Pyrococcus horikoshii: molecular cloning and characterization. | Ryu SI, Park CS, Cha J, Woo EJ, Lee SB | 2005 Apr 8 | 15737605 |
| TreT, a novel trehalose glycosyltransferring synthase of the hyperthermophilic archaeon Thermococcus litoralis. | Qu Q, Lee SJ, Boos W | 2004 Nov 12 | 15364950 |
| RHEA:25408 | ADP-alpha-D-glucose + D-glucose = ADP + alpha,alpha-trehalose + H(+) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction | ![]() |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |