EC number:2.4.1.266
| ID: | 2.4.1.266 |
|---|---|
| Description: | Glucosyl-3-phosphoglycerate synthase. |
| Alternative Name: |
GPG synthase. Glucosylphosphoglycerate synthase. |
| Cath: | 3.90.550.10; 3.40.50.1240; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.4.1.266 |
| BRENDA Enzyme Link: | BRENDA 2.4.1.266 |
| KEGG Enzyme Link: | KEGG2.4.1.266 |
| BioCyc Enzyme Link: | BioCyc 2.4.1.266 |
| ExPASy Enzyme Link: | ExPASy2.4.1.266 |
| EC2PDB Enzyme Link: | EC2PDB 2.4.1.266 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.4.1.266 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.4.1.266 |
| IntEnz Enzyme Link: | IntEnz 2.4.1.266 |
| MEDLINE Enzyme Link: | MEDLINE 2.4.1.266 |
EC number:2.4.1.266
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:31311 | 3-phospho-D-glycerate + ADP-alpha-D-glucose = 2-O-(alpha-D-glucopyranosyl)-3-O-phospho-D-glycerate + ADP + H(+) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The effect of carbonic anhydrase inhibition on the velocity of thrombin-stimulated platelet aggregation under physiological conditions. | Siffert W, Fox G, Gros G | 1984 May 31 | 6428406 |
| Identification of the mycobacterial glucosyl-3-phosphoglycerate synthase. | Empadinhas N, Albuquerque L, Mendes V, Macedo-Ribeiro S, da Costa MS | 2008 Mar | 18221489 |
| RHEA:31315 | 3-phospho-D-glycerate + GDP-D-glucose = 2-O-(alpha-D-glucopyranosyl)-3-O-phospho-D-glycerate + GDP + H(+) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The effect of carbonic anhydrase inhibition on the velocity of thrombin-stimulated platelet aggregation under physiological conditions. | Siffert W, Fox G, Gros G | 1984 May 31 | 6428406 |
| Identification of the mycobacterial glucosyl-3-phosphoglycerate synthase. | Empadinhas N, Albuquerque L, Mendes V, Macedo-Ribeiro S, da Costa MS | 2008 Mar | 18221489 |
| RHEA:31319 | 3-phospho-D-glycerate + UDP-alpha-D-glucose = 2-O-(alpha-D-glucopyranosyl)-3-O-phospho-D-glycerate + H(+) + UDP |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The effect of carbonic anhydrase inhibition on the velocity of thrombin-stimulated platelet aggregation under physiological conditions. | Siffert W, Fox G, Gros G | 1984 May 31 | 6428406 |
| Crystal structure of a UDP-glucose-specific glycosyltransferase from a Mycobacterium species. | Fulton Z, McAlister A, Wilce MC, Brammananth R, Zaker-Tabrizi L, Perugini MA, Bottomley SP, Coppel RL, Crellin PK, Rossjohn J, Beddoe T | 2008 Oct 10 | 18667419 |
| Identification of the mycobacterial glucosyl-3-phosphoglycerate synthase. | Empadinhas N, Albuquerque L, Mendes V, Macedo-Ribeiro S, da Costa MS | 2008 Mar | 18221489 |
| RHEA:47244 | 3-phospho-D-glycerate + an NDP-alpha-D-glucose = 2-O-(alpha-D-glucopyranosyl)-3-O-phospho-D-glycerate + a ribonucleoside 5'-diphosphate + H(+) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The effect of carbonic anhydrase inhibition on the velocity of thrombin-stimulated platelet aggregation under physiological conditions. | Siffert W, Fox G, Gros G | 1984 May 31 | 6428406 |
| Two alternative pathways for the synthesis of the rare compatible solute mannosylglucosylglycerate in Petrotoga mobilis. | Fernandes C, Mendes V, Costa J, Empadinhas N, Jorge C, Lamosa P, Santos H, da Costa MS | 2010 Mar | 20061481 |
| Crystal structure of a UDP-glucose-specific glycosyltransferase from a Mycobacterium species. | Fulton Z, McAlister A, Wilce MC, Brammananth R, Zaker-Tabrizi L, Perugini MA, Bottomley SP, Coppel RL, Crellin PK, Rossjohn J, Beddoe T | 2008 Oct 10 | 18667419 |
| Identification of the mycobacterial glucosyl-3-phosphoglycerate synthase. | Empadinhas N, Albuquerque L, Mendes V, Macedo-Ribeiro S, da Costa MS | 2008 Mar | 18221489 |
| Glucosylglycerate biosynthesis in the deepest lineage of the Bacteria: characterization of the thermophilic proteins GpgS and GpgP from Persephonella marina. | Costa J, Empadinhas N, da Costa MS | 2007 Mar | 17189358 |
| Characterization of the biosynthetic pathway of glucosylglycerate in the archaeon Methanococcoides burtonii. | Costa J, Empadinhas N, Gonçalves L, Lamosa P, Santos H, da Costa MS | 2006 Feb | 16428406 |