Enzyme

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     2. Transferases
        2.4 Glycosyltransferases
            2.4.1 Hexosyltransferases
ID:2.4.1.275
Description:Neolactotriaosylceramide beta-1,4-galactosyltransferase.
Alternative Name: Lactotriaosylceramide beta-1,4-galactosyltransferase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.1.275
BRENDA Enzyme Link: BRENDA 2.4.1.275
KEGG Enzyme Link: KEGG2.4.1.275
BioCyc Enzyme Link: BioCyc 2.4.1.275
ExPASy Enzyme Link: ExPASy2.4.1.275
EC2PDB Enzyme Link: EC2PDB 2.4.1.275
ExplorEnz Enzyme Link: ExplorEnz 2.4.1.275
PRIAM enzyme-specific profiles Link: PRIAM 2.4.1.275
IntEnz Enzyme Link: IntEnz 2.4.1.275
MEDLINE Enzyme Link: MEDLINE 2.4.1.275
MSA:

2.4.1.275;

Phylogenetic Tree:

2.4.1.275;

Uniprot:
M-CSA:
RHEA:31499 beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-N-acylsphing-4-enine + UDP-alpha-D-galactose = beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-N-acylsphing-4-enine + H(+) + UDP
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:6]-[O;H0;+0:7]-[CH;+0:3](-[*:4])-[*:5].[*:1]-[OH;+0:2]
Reaction
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References

TitleAuthorsDatePubMed ID
Cloning of a novel member of the UDP-galactose:beta-N-acetylglucosamine beta1,4-galactosyltransferase family, beta4Gal-T4, involved in glycosphingolipid biosynthesis.Schwientek T, Almeida R, Levery SB, Holmes EH, Bennett E, Clausen H1998 Nov 69792633
A family of human beta4-galactosyltransferases. Cloning and expression of two novel UDP-galactose:beta-n-acetylglucosamine beta1, 4-galactosyltransferases, beta4Gal-T2 and beta4Gal-T3.Almeida R, Amado M, David L, Levery SB, Holmes EH, Merkx G, van Kessel AG, Rygaard E, Hassan H, Bennett E, Clausen H1997 Dec 199405390