ID: | 2.4.1.277 |
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Description: | 10-deoxymethynolide desosaminyltransferase. |
Alternative Name: |
Glycosyltransferase DesVII. |
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 2.4.1.277 |
BRENDA Enzyme Link: | BRENDA 2.4.1.277 |
KEGG Enzyme Link: | KEGG2.4.1.277 |
BioCyc Enzyme Link: | BioCyc 2.4.1.277 |
ExPASy Enzyme Link: | ExPASy2.4.1.277 |
EC2PDB Enzyme Link: | EC2PDB 2.4.1.277 |
ExplorEnz Enzyme Link: | ExplorEnz 2.4.1.277 |
PRIAM enzyme-specific profiles Link: | PRIAM 2.4.1.277 |
IntEnz Enzyme Link: | IntEnz 2.4.1.277 |
MEDLINE Enzyme Link: | MEDLINE 2.4.1.277 |
MSA: | |
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Phylogenetic Tree: | |
Uniprot: | |
M-CSA: |
RHEA:31627 | 10-deoxymethynolide + dTDP-alpha-D-desosamine = 10-deoxymethymycin + dTDP + H(+) |
RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
Reaction | ![]() |
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Title | Authors | Date | PubMed ID |
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Characterization of glycosyltransferase DesVII and its auxiliary partner protein DesVIII in the methymycin/picromycin biosynthetic pathway. | Borisova SA, Liu HW | 2010 Sep 21 | 20695498 |
Glycosylation of acyclic and cyclic aglycone substrates by macrolide glycosyltransferase DesVII/DesVIII: analysis and implications. | Borisova SA, Kim HJ, Pu X, Liu HW | 2008 Jul 2 | 18548476 |
Functional analysis of desVIII homologues involved in glycosylation of macrolide antibiotics by interspecies complementation. | Hong JS, Park SJ, Parajuli N, Park SR, Koh HS, Jung WS, Choi CY, Yoon YJ | 2007 Jan 15 | 17049185 |
Characterization of the glycosyltransferase activity of desVII: analysis of and implications for the biosynthesis of macrolide antibiotics. | Borisova SA, Zhao L, Melançon III CE, Kao CL, Liu HW | 2004 Jun 2 | 15161264 |