| ID: | 2.4.1.277 |
|---|---|
| Description: | 10-deoxymethynolide desosaminyltransferase. |
| Alternative Name: |
Glycosyltransferase DesVII. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 2.4.1.277 |
| BRENDA Enzyme Link: | BRENDA 2.4.1.277 |
| KEGG Enzyme Link: | KEGG2.4.1.277 |
| BioCyc Enzyme Link: | BioCyc 2.4.1.277 |
| ExPASy Enzyme Link: | ExPASy2.4.1.277 |
| EC2PDB Enzyme Link: | EC2PDB 2.4.1.277 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.4.1.277 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.4.1.277 |
| IntEnz Enzyme Link: | IntEnz 2.4.1.277 |
| MEDLINE Enzyme Link: | MEDLINE 2.4.1.277 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:31627 | 10-deoxymethynolide + dTDP-alpha-D-desosamine = 10-deoxymethymycin + dTDP + H(+) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction | ![]() |
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| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characterization of glycosyltransferase DesVII and its auxiliary partner protein DesVIII in the methymycin/picromycin biosynthetic pathway. | Borisova SA, Liu HW | 2010 Sep 21 | 20695498 |
| Glycosylation of acyclic and cyclic aglycone substrates by macrolide glycosyltransferase DesVII/DesVIII: analysis and implications. | Borisova SA, Kim HJ, Pu X, Liu HW | 2008 Jul 2 | 18548476 |
| Functional analysis of desVIII homologues involved in glycosylation of macrolide antibiotics by interspecies complementation. | Hong JS, Park SJ, Parajuli N, Park SR, Koh HS, Jung WS, Choi CY, Yoon YJ | 2007 Jan 15 | 17049185 |
| Characterization of the glycosyltransferase activity of desVII: analysis of and implications for the biosynthesis of macrolide antibiotics. | Borisova SA, Zhao L, Melançon III CE, Kao CL, Liu HW | 2004 Jun 2 | 15161264 |