EC number:2.4.1.302

Enzyme

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EC Tree
     2. Transferases
        2.4 Glycosyltransferases
            2.4.1 Hexosyltransferases
ID:2.4.1.302
Description:L-demethylnoviosyl transferase.
Alternative Name: L-noviosyl transferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.1.302
BRENDA Enzyme Link: BRENDA 2.4.1.302
KEGG Enzyme Link: KEGG2.4.1.302
BioCyc Enzyme Link: BioCyc 2.4.1.302
ExPASy Enzyme Link: ExPASy2.4.1.302
EC2PDB Enzyme Link: EC2PDB 2.4.1.302
ExplorEnz Enzyme Link: ExplorEnz 2.4.1.302
PRIAM enzyme-specific profiles Link: PRIAM 2.4.1.302
IntEnz Enzyme Link: IntEnz 2.4.1.302
MEDLINE Enzyme Link: MEDLINE 2.4.1.302

EC number:2.4.1.302

MSA:

2.4.1.302;
Phylogenetic Tree:

2.4.1.302;
Uniprot:
M-CSA:
RHEA:36695 dTDP-4-O-demethyl-beta-L-noviose + novobiocic acid = desmethyldescarbamoylnovobiocin + dTDP + H(+)
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2]
Reaction
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References

TitleAuthorsDatePubMed ID
Initial characterization of novobiocic acid noviosyl transferase activity of NovM in biosynthesis of the antibiotic novobiocin.Freel Meyers CL, Oberthür M, Anderson JW, Kahne D, Walsh CT2003 Apr 1512680772
Substrate specificity of NovM: implications for novobiocin biosynthesis and glycorandomization.Albermann C, Soriano A, Jiang J, Vollmer H, Biggins JB, Barton WA, Lesniak J, Nikolov DB, Thorson JS2003 Mar 2012633109