EC number:2.4.1.310

Enzyme

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EC Tree
     2. Transferases
        2.4 Glycosyltransferases
            2.4.1 Hexosyltransferases
ID:2.4.1.310
Description:Vancomycin aglycone glucosyltransferase.
Cath: 3.40.50.20; 3.40.50.200; 3.40.50.2000;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.1.310
BRENDA Enzyme Link: BRENDA 2.4.1.310
KEGG Enzyme Link: KEGG2.4.1.310
BioCyc Enzyme Link: BioCyc 2.4.1.310
ExPASy Enzyme Link: ExPASy2.4.1.310
EC2PDB Enzyme Link: EC2PDB 2.4.1.310
ExplorEnz Enzyme Link: ExplorEnz 2.4.1.310
PRIAM enzyme-specific profiles Link: PRIAM 2.4.1.310
IntEnz Enzyme Link: IntEnz 2.4.1.310
MEDLINE Enzyme Link: MEDLINE 2.4.1.310

EC number:2.4.1.310

MSA:

2.4.1.310;
Phylogenetic Tree:

2.4.1.310;
Uniprot:
M-CSA:
RHEA:38587 UDP-alpha-D-glucose + vancomycin aglycone = devancoaminyl-vancomycin + UDP
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:4]-[*:5].[*:6]-[OH;+0:7]>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:7]-[*:6].[*:5]-[OH;+0:4]
Reaction
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References

TitleAuthorsDatePubMed ID
Structure of the UDP-glucosyltransferase GtfB that modifies the heptapeptide aglycone in the biosynthesis of vancomycin group antibiotics.Mulichak AM, Losey HC, Walsh CT, Garavito RM2001 Jul 311470430
Tandem action of glycosyltransferases in the maturation of vancomycin and teicoplanin aglycones: novel glycopeptides.Losey HC, Peczuh MW, Chen Z, Eggert US, Dong SD, Pelczer I, Kahne D, Walsh CT2001 Apr 1711294642