Enzyme

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EC Tree
     2. Transferases
        2.4 Glycosyltransferases
            2.4.1 Hexosyltransferases
ID:2.4.1.311
Description:dTDP-epi-vancosaminyltransferase.
Cath: 3.40.50.20; 3.40.50.200; 3.40.50.2000;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.1.311
BRENDA Enzyme Link: BRENDA 2.4.1.311
KEGG Enzyme Link: KEGG2.4.1.311
BioCyc Enzyme Link: BioCyc 2.4.1.311
ExPASy Enzyme Link: ExPASy2.4.1.311
EC2PDB Enzyme Link: EC2PDB 2.4.1.311
ExplorEnz Enzyme Link: ExplorEnz 2.4.1.311
PRIAM enzyme-specific profiles Link: PRIAM 2.4.1.311
IntEnz Enzyme Link: IntEnz 2.4.1.311
MEDLINE Enzyme Link: MEDLINE 2.4.1.311
MSA:

2.4.1.311;

Phylogenetic Tree:

2.4.1.311;

Uniprot:
M-CSA:
RHEA:38591 devancoaminyl-vancomycin + dTDP-beta-L-4-epi-vancosamine = chloroorienticin B + dTDP + H(+)
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2]
Reaction
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References

TitleAuthorsDatePubMed ID
Characterization of a regiospecific epivancosaminyl transferase GtfA and enzymatic reconstitution of the antibiotic chloroeremomycin.Lu W, Oberthür M, Leimkuhler C, Tao J, Kahne D, Walsh CT2004 Mar 3015070728
Structure of the TDP-epi-vancosaminyltransferase GtfA from the chloroeremomycin biosynthetic pathway.Mulichak AM, Losey HC, Lu W, Wawrzak Z, Walsh CT, Garavito RM2003 Aug 512874381