EC number:2.4.1.322

Enzyme

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EC Tree
     2. Transferases
        2.4 Glycosyltransferases
            2.4.1 Hexosyltransferases
ID:2.4.1.322
Description:Devancosaminyl-vancomycin vancosaminetransferase.
Alternative Name: Devancosamine-vancomycin TDP-vancosaminyltransferase.
Desvancosaminyl-vancomycin vancosaminetransferase.
Cath: 3.40.50.20; 3.40.50.200; 3.40.50.2000;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.1.322
BRENDA Enzyme Link: BRENDA 2.4.1.322
KEGG Enzyme Link: KEGG2.4.1.322
BioCyc Enzyme Link: BioCyc 2.4.1.322
ExPASy Enzyme Link: ExPASy2.4.1.322
EC2PDB Enzyme Link: EC2PDB 2.4.1.322
ExplorEnz Enzyme Link: ExplorEnz 2.4.1.322
PRIAM enzyme-specific profiles Link: PRIAM 2.4.1.322
IntEnz Enzyme Link: IntEnz 2.4.1.322
MEDLINE Enzyme Link: MEDLINE 2.4.1.322

EC number:2.4.1.322

MSA:

2.4.1.322;
Phylogenetic Tree:

2.4.1.322;
Uniprot:
M-CSA:
RHEA:39891 devancoaminyl-vancomycin + dTDP-beta-L-vancosamine = dTDP + H(+) + vancomycin
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2]
Reaction
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References

TitleAuthorsDatePubMed ID
Crystal structure of vancosaminyltransferase GtfD from the vancomycin biosynthetic pathway: interactions with acceptor and nucleotide ligands.Mulichak AM, Lu W, Losey HC, Walsh CT, Garavito RM2004 May 1115122882
Tandem action of glycosyltransferases in the maturation of vancomycin and teicoplanin aglycones: novel glycopeptides.Losey HC, Peczuh MW, Chen Z, Eggert US, Dong SD, Pelczer I, Kahne D, Walsh CT2001 Apr 1711294642