Enzyme

Download
EC Tree
     2. Transferases
        2.4 Glycosyltransferases
            2.4.1 Hexosyltransferases
ID:2.4.1.38
Description:Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase.
Alternative Name: UDP-galactose--glycoprotein galactosyltransferase.
Thyroid galactosyltransferase.
Glycoprotein 4-beta-galactosyltransferase.
GalT.
Cath: 3.90.550.10;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.1.38
BRENDA Enzyme Link: BRENDA 2.4.1.38
KEGG Enzyme Link: KEGG2.4.1.38
BioCyc Enzyme Link: BioCyc 2.4.1.38
ExPASy Enzyme Link: ExPASy2.4.1.38
EC2PDB Enzyme Link: EC2PDB 2.4.1.38
ExplorEnz Enzyme Link: ExplorEnz 2.4.1.38
PRIAM enzyme-specific profiles Link: PRIAM 2.4.1.38
IntEnz Enzyme Link: IntEnz 2.4.1.38
MEDLINE Enzyme Link: MEDLINE 2.4.1.38
MSA:

2.4.1.38;

Phylogenetic Tree:

2.4.1.38;

Uniprot:
M-CSA:
RHEA:22932 an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2]
Reaction
Core-to-Core More
Core-to-Core More
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Biosynthesis of terminal Gal alpha 1----3Gal beta 1----4GlcNAc-R oligosaccharide sequences on glycoconjugates. Purification and acceptor specificity of a UDP-Gal:N-acetyllactosaminide alpha 1----3-galactosyltransferase from calf thymus.Blanken WM, Van den Eijnden DH1985 Oct 253932335
Biosynthesis of blood-group I and i substances. Specificity of bovine colostrum beta-N-acetyl-D-glucosaminide beta 1 leads to 4 galactosyltransferase.Blanken WM, Hooghwinkel GJ, Van Den Eijnden DH1982 Oct6816588
Glycosyltransferases and their use in assessing oligosaccharide structure and structure-function relationships.Beyer TA, Sadler JE, Rearick JI, Paulson JC, Hill RL19816784450