Enzyme

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     2. Transferases
        2.4 Glycosyltransferases
            2.4.1 Hexosyltransferases
ID:2.4.1.41
Description:Polypeptide N-acetylgalactosaminyltransferase.
Alternative Name: Protein-UDP acetylgalactosaminyltransferase.
Cath: 1.10.8.460; 3.90.550.10; 2.80.10.50;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.1.41
BRENDA Enzyme Link: BRENDA 2.4.1.41
KEGG Enzyme Link: KEGG2.4.1.41
BioCyc Enzyme Link: BioCyc 2.4.1.41
ExPASy Enzyme Link: ExPASy2.4.1.41
EC2PDB Enzyme Link: EC2PDB 2.4.1.41
ExplorEnz Enzyme Link: ExplorEnz 2.4.1.41
PRIAM enzyme-specific profiles Link: PRIAM 2.4.1.41
IntEnz Enzyme Link: IntEnz 2.4.1.41
MEDLINE Enzyme Link: MEDLINE 2.4.1.41
MSA:

2.4.1.41;

Phylogenetic Tree:

2.4.1.41;

Uniprot:
M-CSA:
RHEA:52424 L-threonyl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = H(+) + O(3)-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2]
Reaction
Core-to-Core More
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References

TitleAuthorsDatePubMed ID
cDNA cloning and expression of a novel UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase.Hagen FK, Ten Hagen KG, Beres TM, Balys MM, VanWuyckhuyse BC, Tabak LA1997 May 239153242
Isolation and expression of a cDNA clone encoding a bovine UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase.Homa FL, Hollander T, Lehman DJ, Thomsen DR, Elhammer AP1993 Jun 157685345
Purification and cDNA cloning of a human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase.White T, Bennett EP, Takio K, Sørensen T, Bonding N, Clausen H1995 Oct 137592619
Purification and characterization of UDP-GalNAc:polypeptide N-acetylgalactosamine transferase from an ascites hepatoma, AH 66.Sugiura M, Kawasaki T, Yamashina I1982 Aug 256809738
Dynamic association between the catalytic and lectin domains of human UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase-2.Fritz TA, Raman J, Tabak LA2006 Mar 3116434399

RHEA:23956 L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = H(+) + O(3)-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2]
Reaction
Core-to-Core More
Core-to-Core More

References

TitleAuthorsDatePubMed ID
cDNA cloning and expression of a novel UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase.Hagen FK, Ten Hagen KG, Beres TM, Balys MM, VanWuyckhuyse BC, Tabak LA1997 May 239153242
Isolation and expression of a cDNA clone encoding a bovine UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase.Homa FL, Hollander T, Lehman DJ, Thomsen DR, Elhammer AP1993 Jun 157685345
Purification and cDNA cloning of a human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase.White T, Bennett EP, Takio K, Sørensen T, Bonding N, Clausen H1995 Oct 137592619
Purification and characterization of UDP-GalNAc:polypeptide N-acetylgalactosamine transferase from an ascites hepatoma, AH 66.Sugiura M, Kawasaki T, Yamashina I1982 Aug 256809738
Dynamic association between the catalytic and lectin domains of human UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase-2.Fritz TA, Raman J, Tabak LA2006 Mar 3116434399