Enzyme

Download
EC Tree
     2. Transferases
        2.4 Glycosyltransferases
            2.4.1 Hexosyltransferases
ID:2.4.1.46
Description:Monogalactosyldiacylglycerol synthase.
Alternative Name: Uridine diphosphogalactose-1,2-diacylglycerol galactosyltransferase.
UDPgalactose:1,2-diacylglycerol 3-beta-D-galactosyltransferase.
UDP-galactose:diacylglycerol galactosyltransferase.
UDP-galactose-diacylglyceride galactosyltransferase.
UDP galactose-1,2-diacylglycerol galactosyltransferase.
MGDG synthase.
1-beta-MGDG.
1,2-diacylglycerol 3-beta-galactosyltransferase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.1.46
BRENDA Enzyme Link: BRENDA 2.4.1.46
KEGG Enzyme Link: KEGG2.4.1.46
BioCyc Enzyme Link: BioCyc 2.4.1.46
ExPASy Enzyme Link: ExPASy2.4.1.46
EC2PDB Enzyme Link: EC2PDB 2.4.1.46
ExplorEnz Enzyme Link: ExplorEnz 2.4.1.46
PRIAM enzyme-specific profiles Link: PRIAM 2.4.1.46
IntEnz Enzyme Link: IntEnz 2.4.1.46
MEDLINE Enzyme Link: MEDLINE 2.4.1.46
MSA:

2.4.1.46;

Phylogenetic Tree:

2.4.1.46;

Uniprot:
M-CSA:
RHEA:14945 a 1,2-diacyl-sn-glycerol + UDP-alpha-D-galactose = a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+) + UDP
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2]
Reaction
Core-to-Core More
Core-to-Core More

References

TitleAuthorsDatePubMed ID
The metabolism of glyceride glycolipids. II. Biosynthesis of monogalactosyl diglyceride from uridine diphosphate galactose and diglyceride in brain.Wenger DA, Petitpas JW, Pieringer RA1968 Oct5681471
Biochemical changes in Bifidobacterium bifidum var. pennsylvanicus after cell-wall inhibition. VI. Biosynthesis of the galactosyldiglycerides.Veerkamp JH1974 Apr 264838219
Expression and characterization of a Mycoplasma genitalium glycosyltransferase in membrane glycolipid biosynthesis: potential target against mycoplasma infections.Andrés E, Martínez N, Planas A2011 Oct 1421835921
A processive lipid glycosyltransferase in the small human pathogen Mycoplasma pneumoniae: involvement in host immune response.Klement ML, Ojemyr L, Tagscherer KE, Widmalm G, Wieslander A2007 Sep17697098
Three enzyme systems for galactoglycerolipid biosynthesis are coordinately regulated in plants.Benning C, Ohta H2005 Jan 2815590685
Biochemical and topological properties of type A MGDG synthase, a spinach chloroplast envelope enzyme catalyzing the synthesis of both prokaryotic and eukaryotic MGDG.Miège C, Maréchal E, Shimojima M, Awai K, Block MA, Ohta H, Takamiya K, Douce R, Joyard J1999 Nov10518794