Enzyme

Download
EC Tree
     2. Transferases
        2.4 Glycosyltransferases
            2.4.1 Hexosyltransferases
ID:2.4.1.62
Description:Ganglioside galactosyltransferase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.1.62
BRENDA Enzyme Link: BRENDA 2.4.1.62
KEGG Enzyme Link: KEGG2.4.1.62
BioCyc Enzyme Link: BioCyc 2.4.1.62
ExPASy Enzyme Link: ExPASy2.4.1.62
EC2PDB Enzyme Link: EC2PDB 2.4.1.62
ExplorEnz Enzyme Link: ExplorEnz 2.4.1.62
PRIAM enzyme-specific profiles Link: PRIAM 2.4.1.62
IntEnz Enzyme Link: IntEnz 2.4.1.62
MEDLINE Enzyme Link: MEDLINE 2.4.1.62
MSA:

2.4.1.62;

Phylogenetic Tree:

2.4.1.62;

Uniprot:
M-CSA:
RHEA:16773 ganglioside GM2 (d18:1(4E)) + UDP-alpha-D-galactose = ganglioside GM1 (d18:1(4E)) + H(+) + UDP
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:4]-[*:5].[*:6]-[OH;+0:7]>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:7]-[*:6].[*:5]-[OH;+0:4]
Reaction
Core-to-Core More
Core-to-Core More
Core-to-Core More

References

TitleAuthorsDatePubMed ID
A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta-nacetyl-galactosamine beta-1,3-galactosyltransferase family.Amado M, Almeida R, Carneiro F, Levery SB, Holmes EH, Nomoto M, Hollingsworth MA, Hassan H, Schwientek T, Nielsen PA, Bennett EP, Clausen H1998 May 229582303
Expression cloning of rat cDNA encoding UDP-galactose:GD2 beta1,3-galactosyltransferase that determines the expression of GD1b/GM1/GA1.Miyazaki H, Fukumoto S, Okada M, Hasegawa T, Furukawa K1997 Oct 39312075
Frog brain uridine diphosphate galactose-N-acetylgalactosaminyl-N-acetylneuraminylgalactosylglucosylceramide galactosyltransferase.Yip MC, Dain JA1970 Jun5484669
The enzymic synthesis of ganglioside. II. UDP-galactose: N-acetylgalactosaminyl-(N-acetylneuraminyl)galactosyl-glucosyl-ceramide galactosyltransferase in rat brain.Yip GB, Dain JA1970 May 134987145
Mouse beta 1,3-galactosyltransferase (GA1/GM1/GD1b synthase): protein characterization, tissue expression, and developmental regulation in neural retina.Daniotti JL, Martina JA, Zurita AR, Maccioni HJ1999 Oct 1510502288