Enzyme

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EC Tree
     2. Transferases
        2.4 Glycosyltransferases
            2.4.1 Hexosyltransferases
ID:2.4.1.66
Description:Procollagen glucosyltransferase.
Alternative Name: Galactosylhydroxylysine-glucosyltransferase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.1.66
BRENDA Enzyme Link: BRENDA 2.4.1.66
KEGG Enzyme Link: KEGG2.4.1.66
BioCyc Enzyme Link: BioCyc 2.4.1.66
ExPASy Enzyme Link: ExPASy2.4.1.66
EC2PDB Enzyme Link: EC2PDB 2.4.1.66
ExplorEnz Enzyme Link: ExplorEnz 2.4.1.66
PRIAM enzyme-specific profiles Link: PRIAM 2.4.1.66
IntEnz Enzyme Link: IntEnz 2.4.1.66
MEDLINE Enzyme Link: MEDLINE 2.4.1.66
MSA:

2.4.1.66;

Phylogenetic Tree:

2.4.1.66;

Uniprot:
M-CSA:
RHEA:12576 (5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[procollagen] + UDP-alpha-D-glucose = (5R)-5-O-[alpha-D-glucosyl-(1->2)-beta-D-galactosyl]-5-hydroxy-L-lysyl-[procollagen] + H(+) + UDP
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2]
Reaction
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References

TitleAuthorsDatePubMed ID
Attachment of carbohydrate to collagen. Isolation, purification and properties of the glucosyl transferase.Bosmann HB, Eylar EH1968 Jan 115637038
Collagen-glucosyl transferase in fibriblasts transformed by oncogenic viruses.Bosmann HB, Eylar EH1968 May 114968368
Evidence for the linkage of a disaccharide to hydroxylysine in tropocollagen.Butler WT, Cunningham LW1966 Sep 104288358
Lysyl hydroxylase 3 glucosylates galactosylhydroxylysine residues in type I collagen in osteoblast culture.Sricholpech M, Perdivara I, Nagaoka H, Yokoyama M, Tomer KB, Yamauchi M2011 Mar 1821220425