EC number:2.4.1.79
| ID: | 2.4.1.79 |
|---|---|
| Description: | Globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase. |
| Alternative Name: |
Uridine diphosphoacetylgalactosamine-galactosylgalactosylglucosylceramide Globoside synthetase. Globoside synthase. acetylgalactosaminyltransferase. Galactosylgalactosylglucosylceramide beta-D- Beta-3GalNAc-T1. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.4.1.79 |
| BRENDA Enzyme Link: | BRENDA 2.4.1.79 |
| KEGG Enzyme Link: | KEGG2.4.1.79 |
| BioCyc Enzyme Link: | BioCyc 2.4.1.79 |
| ExPASy Enzyme Link: | ExPASy2.4.1.79 |
| EC2PDB Enzyme Link: | EC2PDB 2.4.1.79 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.4.1.79 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.4.1.79 |
| IntEnz Enzyme Link: | IntEnz 2.4.1.79 |
| MEDLINE Enzyme Link: | MEDLINE 2.4.1.79 |
| RHEA:22252 | globoside Gb3Cer (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = globoside Gb4Cer (d18:1(4E)) + H(+) + UDP |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:6]-[O;H0;+0:7]-[CH;+0:3](-[*:4])-[*:5].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and characterization of UDP-N-acetylgalactosamine: globotriaosylceramide beta-3-N-acetylgalactosaminyltransferase, a synthase of human blood group P antigen, from canine spleen. | Taniguchi N, Makita A | 1984 May 10 | 6425294 |
| Biosynthesis of a globoside-type glycosphingolipid by a -N-acetylgalactosaminyltransferase from embryonic chicken brain. | Chien JL, Williams T, Basu S | 1973 Mar 10 | 4632917 |
| Biosynthesis of globoside and Forssman hapten from trihexosylceramide and properties of beta-N-acetyl-galactosaminyltransferase of guinea pig kidney. | Ishibashi T, Kijimoto S, Makita A | 1974 Jan 23 | 4433547 |
| Expression cloning of human globoside synthase cDNAs. Identification of beta 3Gal-T3 as UDP-N-acetylgalactosamine:globotriaosylceramide beta 1,3-N-acetylgalactosaminyltransferase. | Okajima T, Nakamura Y, Uchikawa M, Haslam DB, Numata SI, Furukawa K, Urano T, Furukawa K | 2000 Dec 22 | 10993897 |