Enzyme

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     2. Transferases
        2.4 Glycosyltransferases
            2.4.1 Hexosyltransferases
ID:2.4.1.83
Description:Dolichyl-phosphate beta-D-mannosyltransferase.
Alternative Name: Mannosylphosphoryldolichol synthase.
Mannosylphosphodolichol synthase.
Dolichol-phosphate mannosyltransferase.
Dolichol-phosphate mannose synthase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.1.83
BRENDA Enzyme Link: BRENDA 2.4.1.83
KEGG Enzyme Link: KEGG2.4.1.83
BioCyc Enzyme Link: BioCyc 2.4.1.83
ExPASy Enzyme Link: ExPASy2.4.1.83
EC2PDB Enzyme Link: EC2PDB 2.4.1.83
ExplorEnz Enzyme Link: ExplorEnz 2.4.1.83
PRIAM enzyme-specific profiles Link: PRIAM 2.4.1.83
IntEnz Enzyme Link: IntEnz 2.4.1.83
MEDLINE Enzyme Link: MEDLINE 2.4.1.83
MSA:

2.4.1.83;

Phylogenetic Tree:

2.4.1.83;

Uniprot:
M-CSA:
RHEA:21184 dolichyl phosphate + GDP-alpha-D-mannose = dolichyl beta-D-mannosyl phosphate + GDP
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2]
Reaction
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References

TitleAuthorsDatePubMed ID
Yeast mannosyl transferases requiring dolichyl phosphate and dolichyl phosphate mannose as substrate. Partial purification and characterization of the solubilized enzyme.Babczinski P, Haselbeck A, Tanner W1980 Apr6989607
GDPmannose dolicholphosphate mannosyltransferase of chicken liver mitochondria.Tomita Y, Motokawa Y1985 Oct 174052454
Purification of GDP mannose:dolichyl-phosphate O-beta-D-mannosyltransferase from Saccharomyces cerevisiae.Haselbeck A1989 May 152659345
In vitro phosphorylation by cAMP-dependent protein kinase up-regulates recombinant Saccharomyces cerevisiae mannosylphosphodolichol synthase.Banerjee DK, Carrasquillo EA, Hughey P, Schutzbach JS, Martínez JA, Baksi K2005 Feb 1115548536
Ppm1, a novel polyprenol monophosphomannose synthase from Mycobacterium tuberculosis.Gurcha SS, Baulard AR, Kremer L, Locht C, Moody DB, Muhlecker W, Costello CE, Crick DC, Brennan PJ, Besra GS2002 Jul 1511931640