EC number:2.4.1.86
| ID: | 2.4.1.86 |
|---|---|
| Description: | N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase. |
| Alternative Name: |
Paragloboside synthase. Lactotriaosylceramide 4-beta-galactosyltransferase. Glucosaminylgalactosylglucosylceramide beta-galactosyltransferase. Glucosaminylgalactosylglucosylceramide 4-beta-galactosyltransferase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.4.1.86 |
| BRENDA Enzyme Link: | BRENDA 2.4.1.86 |
| KEGG Enzyme Link: | KEGG2.4.1.86 |
| BioCyc Enzyme Link: | BioCyc 2.4.1.86 |
| ExPASy Enzyme Link: | ExPASy2.4.1.86 |
| EC2PDB Enzyme Link: | EC2PDB 2.4.1.86 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.4.1.86 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.4.1.86 |
| IntEnz Enzyme Link: | IntEnz 2.4.1.86 |
| MEDLINE Enzyme Link: | MEDLINE 2.4.1.86 |
| RHEA:53432 | an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Enzymatic synthesis of a tetraglycosylceramide by a galactosyltransferase from rabbit bone marrow. | Basu M, Basu S | 1972 Mar 10 | 4335001 |
| Differential activities of glycolipid glycosyltransferases in Tay-Sachs disease: studies in cultured cells from cerebrum. | Basu M, Presper KA, Basu S, Hoffman LM, Brooks SE | 1979 Sep | 291963 |
| Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions. | Amado M, Almeida R, Schwientek T, Clausen H | 1999 Dec 6 | 10580128 |
| Differential expression of beta1,3galactosyltransferases in human colon cells derived from adenocarcinomas or normal mucosa. | Bardoni A, Valli M, Trinchera M | 1999 May 14 | 10356986 |
| A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta-nacetyl-galactosamine beta-1,3-galactosyltransferase family. | Amado M, Almeida R, Carneiro F, Levery SB, Holmes EH, Nomoto M, Hollingsworth MA, Hassan H, Schwientek T, Nielsen PA, Bennett EP, Clausen H | 1998 May 22 | 9582303 |
| RHEA:16045 | beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-N-acylsphing-4-enine + UDP-alpha-D-galactose = beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-N-acylsphing-4-enine + H(+) + UDP |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:6]-[O;H0;+0:7]-[CH;+0:3](-[*:4])-[*:5].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta-nacetyl-galactosamine beta-1,3-galactosyltransferase family. | Amado M, Almeida R, Carneiro F, Levery SB, Holmes EH, Nomoto M, Hollingsworth MA, Hassan H, Schwientek T, Nielsen PA, Bennett EP, Clausen H | 1998 May 22 | 9582303 |