EC number:2.4.1.87
| ID: | 2.4.1.87 |
|---|---|
| Description: | N-acetyllactosaminide 3-alpha-galactosyltransferase. |
| Alternative Name: |
glucosylceramide galactosyltransferase. Uridine diphosphogalactose-galactosylacetylglucosaminylgalactosyl- Uridine diphosphogalactose-acetyllactosamine galactosyltransferase. 1->3-galactosyltransferase. Uridine diphosphogalactose-acetyllactosamine alpha- glycopeptide alpha-1,3-D-galactosyltransferase. UDPgalactose:beta-D-galactosyl-beta-1,4-N-acetyl-D-glucosaminyl- UDP-galactose-acetyllactosamine alpha-D-galactosyltransferase. UDP-Gal:N-acetyllactosaminide alpha-1,3-D-galactosyltransferase. UDP-Gal:Gal-beta-1->4GlcNAc-R alpha-1->3-galactosyltransferase. N-acetyllactosaminide alpha-1,3-galactosyltransferase. Glucosaminylglycopeptide alpha-1,3-galactosyltransferase. Galactosyltransferase. galactosyltransferase. Beta-D-galactosyl-N-acetylglucosaminylglycopeptide alpha-1,3- Alpha-galactosyltransferase. |
| Cath: | 3.90.550.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.4.1.87 |
| BRENDA Enzyme Link: | BRENDA 2.4.1.87 |
| KEGG Enzyme Link: | KEGG2.4.1.87 |
| BioCyc Enzyme Link: | BioCyc 2.4.1.87 |
| ExPASy Enzyme Link: | ExPASy2.4.1.87 |
| EC2PDB Enzyme Link: | EC2PDB 2.4.1.87 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.4.1.87 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.4.1.87 |
| IntEnz Enzyme Link: | IntEnz 2.4.1.87 |
| MEDLINE Enzyme Link: | MEDLINE 2.4.1.87 |
| RHEA:13013 | a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose = an alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| An alpha-D-galactosyltransferase activity in Ehrlich ascites tumor cells. Biosynthesis and characterization of a trisaccharide (alpha-D-galactose-(1 goes to 3)-N-acetyllactosamine). | Blake DA, Goldstein IJ | 1981 Jun 10 | 6787040 |
| Enzymatic synthesis of a blood group B-related pentaglycosylceramide by an alpha-galactosyltransferase from rabbit bone marrow. | Basu M, Basu S | 1973 Mar 10 | 4632915 |
| Biosynthesis of terminal Gal alpha 1----3Gal beta 1----4GlcNAc-R oligosaccharide sequences on glycoconjugates. Purification and acceptor specificity of a UDP-Gal:N-acetyllactosaminide alpha 1----3-galactosyltransferase from calf thymus. | Blanken WM, Van den Eijnden DH | 1985 Oct 25 | 3932335 |
| Site-directed mutagenesis of glutamate 317 of bovine alpha-1,3Galactosyltransferase and its effect on enzyme activity: implications for reaction mechanism. | Molina P, Knegtel RM, Macher BA | 2007 Aug | 17574762 |
| Fold recognition study of alpha3-galactosyltransferase and molecular modeling of the nucleotide sugar-binding domain. | Imberty A, Monier C, Bettler E, Morera S, Freemont P, Sippl M, Flöckner H, Rüger W, Breton C | 1999 Jul | 10362841 |