Enzyme

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     2. Transferases
        2.4 Glycosyltransferases
            2.4.1 Hexosyltransferases
ID:2.4.1.88
Description:Globoside alpha-N-acetylgalactosaminyltransferase.
Alternative Name: Forssman synthase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.1.88
BRENDA Enzyme Link: BRENDA 2.4.1.88
KEGG Enzyme Link: KEGG2.4.1.88
BioCyc Enzyme Link: BioCyc 2.4.1.88
ExPASy Enzyme Link: ExPASy2.4.1.88
EC2PDB Enzyme Link: EC2PDB 2.4.1.88
ExplorEnz Enzyme Link: ExplorEnz 2.4.1.88
PRIAM enzyme-specific profiles Link: PRIAM 2.4.1.88
IntEnz Enzyme Link: IntEnz 2.4.1.88
MEDLINE Enzyme Link: MEDLINE 2.4.1.88
MSA:

2.4.1.88;

Phylogenetic Tree:

2.4.1.88;

Uniprot:
M-CSA:
RHEA:22164 globoside Gb4Cer (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = globoside Forssman (d18:1(4E)) + H(+) + UDP
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:4]-[*:5].[*:6]-[OH;+0:7]>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:7]-[*:6].[*:5]-[OH;+0:4]
Reaction
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References

TitleAuthorsDatePubMed ID
Expression cloning of Forssman glycolipid synthetase: a novel member of the histo-blood group ABO gene family.Haslam DB, Baenziger JU1996 Oct 18855242
Biosynthesis of Forssman hapten from globoside by alpha-N-acetylgalactosaminyltransferase of guinea pig tissues.Kijimoto S, Ishibashi T, Makita A1974 Jan4823436
Molecular modeling of glycosyltransferases involved in the biosynthesis of blood group A, blood group B, Forssman, and iGb3 antigens and their interaction with substrates.Heissigerova H, Breton C, Moravcova J, Imberty A2003 May12626391