EC number:2.4.1.90
| ID: | 2.4.1.90 |
|---|---|
| Description: | N-acetyllactosamine synthase. |
| Alternative Name: |
UDP-galactose-N-acetylglucosamine beta-D-galactosyltransferase. UDP-galactose--N-acetylglucosamine beta-D-galactosyltransferase. NAL synthetase. N-acetylglucosamine (beta-1,4)galactosyltransferase. Acetyllactosamine synthetase. |
| Cath: | 3.90.550.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.4.1.90 |
| BRENDA Enzyme Link: | BRENDA 2.4.1.90 |
| KEGG Enzyme Link: | KEGG2.4.1.90 |
| BioCyc Enzyme Link: | BioCyc 2.4.1.90 |
| ExPASy Enzyme Link: | ExPASy2.4.1.90 |
| EC2PDB Enzyme Link: | EC2PDB 2.4.1.90 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.4.1.90 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.4.1.90 |
| IntEnz Enzyme Link: | IntEnz 2.4.1.90 |
| MEDLINE Enzyme Link: | MEDLINE 2.4.1.90 |
| RHEA:17745 | N-acetyl-D-glucosamine + UDP-alpha-D-galactose = beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + H(+) + UDP |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Cloning of a novel member of the UDP-galactose:beta-N-acetylglucosamine beta1,4-galactosyltransferase family, beta4Gal-T4, involved in glycosphingolipid biosynthesis. | Schwientek T, Almeida R, Levery SB, Holmes EH, Bennett E, Clausen H | 1998 Nov 6 | 9792633 |
| Isolation and characterization of UDP-galactose:N-acetylglucosamine 4 beta-galactosyltransferase activity induced in rat parotid glands treated with isoproterenol. | Humphreys-Beher MG | 1984 May 10 | 6201486 |
| Galactosyltransfer in mouse mastocytoma: purification and properties of N-acetyllactosamine synthetase. | Helting T, Erbing B | 1973 Jan 12 | 4631039 |
| Bovine galactosyl transferase. Substrate.managanese complexes and the role of manganese ions in the mechanism. | Tsopanakis AD, Herries DG | 1978 Feb 1 | 203458 |
| Structure and catalytic cycle of beta-1,4-galactosyltransferase. | Ramakrishnan B, Boeggeman E, Ramasamy V, Qasba PK | 2004 Oct | 15465321 |
| The role of tryptophan 314 in the conformational changes of beta1,4-galactosyltransferase-I. | Ramasamy V, Ramakrishnan B, Boeggeman E, Qasba PK | 2003 Aug 29 | 12927542 |