Enzyme

Download
EC Tree
     2. Transferases
        2.4 Glycosyltransferases
            2.4.2 Pentosyltransferases
ID:2.4.2.21
Description:Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase.
Alternative Name: phosphoribosyltransferase.
Nicotinate mononucleotide-dimethylbenzimidazole
N(1)-alpha-phosphoribosyltransferase.
Cath: 1.10.1610.10; 3.90.550.10; 3.40.50.10210; 3.40.50.300;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.2.21
BRENDA Enzyme Link: BRENDA 2.4.2.21
KEGG Enzyme Link: KEGG2.4.2.21
BioCyc Enzyme Link: BioCyc 2.4.2.21
ExPASy Enzyme Link: ExPASy2.4.2.21
EC2PDB Enzyme Link: EC2PDB 2.4.2.21
ExplorEnz Enzyme Link: ExplorEnz 2.4.2.21
PRIAM enzyme-specific profiles Link: PRIAM 2.4.2.21
IntEnz Enzyme Link: IntEnz 2.4.2.21
MEDLINE Enzyme Link: MEDLINE 2.4.2.21
MSA:

2.4.2.21;

Phylogenetic Tree:

2.4.2.21;

Uniprot:
M-CSA:
RHEA:11196 5,6-dimethylbenzimidazole + nicotinate beta-D-ribonucleotide = alpha-ribazole 5'-phosphate + H(+) + nicotinate
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[n+;H0:4](:[*:5]):[*:6].[*:7]:[nH;+0:8]:[*:9]>>[*:1]-[CH;+0:2](-[*:3])-[n;H0;+0:8](:[*:7]):[*:9].[*:5]:[n;H0;+0:4]:[*:6]
Reaction
Core-to-Core More
Core-to-Core More
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Capture of a labile substrate by expulsion of water molecules from the active site of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella enterica.Cheong CG, Escalante-Semerena JC, Rayment I2002 Oct 2512101181
Structural investigation of the biosynthesis of alternative lower ligands for cobamides by nicotinate mononucleotide: 5,6-dimethylbenzimidazole phosphoribosyltransferase from Salmonella enterica.Cheong CG, Escalante-Semerena JC, Rayment I2001 Oct 511441022