EC number:2.4.2.22
| ID: | 2.4.2.22 | ||
|---|---|---|---|
| Description: | Xanthine phosphoribosyltransferase. | ||
| Alternative Name: |
XMP pyrophosphorylase. Xanthylic pyrophosphorylase. Xanthylate pyrophosphorylase. Xanthosine 5'-phosphate pyrophosphorylase. Xanthine-guanine phosphoribosyltransferase. Xan phosphoribosyltransferase. | ||
| Prosite: | PDOC00096; | ||
| PDB: |
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| Cath: | 1.10.10.10; 3.40.210.30; 3.40.50.20; 3.40.50.2020; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.4.2.22 |
| BRENDA Enzyme Link: | BRENDA 2.4.2.22 |
| KEGG Enzyme Link: | KEGG2.4.2.22 |
| BioCyc Enzyme Link: | BioCyc 2.4.2.22 |
| ExPASy Enzyme Link: | ExPASy2.4.2.22 |
| EC2PDB Enzyme Link: | EC2PDB 2.4.2.22 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.4.2.22 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.4.2.22 |
| IntEnz Enzyme Link: | IntEnz 2.4.2.22 |
| MEDLINE Enzyme Link: | MEDLINE 2.4.2.22 |
| RHEA:10800 | diphosphate + XMP = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]:[n;H0;+0:4](:[*:5])-[CH;+0:6](-[*:7])-[*:8]>>[*:7]-[CH;+0:6](-[*:8])-[O;H0;+0:2]-[*:1].[*:3]:[nH;+0:4]:[*:5] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Crystal structure of Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase with XMP, pyrophosphate, and two Mg(2+) ions bound: insights into the catalytic mechanism. | Héroux A, White EL, Ross LJ, Davis RL, Borhani DW | 1999 Nov 2 | 10545171 |