EC number:2.4.2.36
| ID: | 2.4.2.36 |
|---|---|
| Description: | NAD(+)--diphthamide ADP-ribosyltransferase. |
| Alternative Name: |
Mono(ADP-ribosyl)transferase. ADP-ribosyltransferase. |
| Cath: | 1.10.490.40; 1.20.5.240; 3.90.1350.10; 3.90.175.10; 3.90.176.10; 3.90.210.10; 2.60.120.20; 2.60.120.200; 2.60.40.700; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.4.2.36 |
| BRENDA Enzyme Link: | BRENDA 2.4.2.36 |
| KEGG Enzyme Link: | KEGG2.4.2.36 |
| BioCyc Enzyme Link: | BioCyc 2.4.2.36 |
| ExPASy Enzyme Link: | ExPASy2.4.2.36 |
| EC2PDB Enzyme Link: | EC2PDB 2.4.2.36 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.4.2.36 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.4.2.36 |
| IntEnz Enzyme Link: | IntEnz 2.4.2.36 |
| MEDLINE Enzyme Link: | MEDLINE 2.4.2.36 |
| RHEA:11820 | diphthamide-[translation elongation factor 2] + NAD(+) = H(+) + N-(ADP-D-ribosyl)diphthamide-[translation elongation factor 2] + nicotinamide |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[n+;H0:4](:[*:5]):[*:6].[*:7]:[nH;+0:8]:[*:9]>>[*:1]-[CH;+0:2](-[*:3])-[n;H0;+0:8](:[*:7]):[*:9].[*:5]:[n;H0;+0:4]:[*:6] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Cellular ADP-ribosyltransferase with the same mechanism of action as diphtheria toxin and Pseudomonas toxin A. | Lee H, Iglewski WJ | 1984 May | 6326138 |
| ADP-ribosylation. | Ueda K, Hayaishi O | 1985 | 3927821 |
| Cholix toxin, a novel ADP-ribosylating factor from Vibrio cholerae. | Jørgensen R, Purdy AE, Fieldhouse RJ, Kimber MS, Bartlett DH, Merrill AR | 2008 Apr 18 | 18276581 |