Enzyme

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     2. Transferases
        2.4 Glycosyltransferases
            2.4.99 Transferring other glycosyl groups
ID:2.4.99.13
Description:(Kdo)-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase.
Alternative Name: Kdo transferase.
3-deoxy-manno-octulosonic acid transferase.
3-deoxy-D-manno-oct-2-ulosonic acid transferase.
Cath: 3.40.50.11720; 3.40.50.20; 3.40.50.200; 3.40.50.2000;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.4.99.13
BRENDA Enzyme Link: BRENDA 2.4.99.13
KEGG Enzyme Link: KEGG2.4.99.13
BioCyc Enzyme Link: BioCyc 2.4.99.13
ExPASy Enzyme Link: ExPASy2.4.99.13
EC2PDB Enzyme Link: EC2PDB 2.4.99.13
ExplorEnz Enzyme Link: ExplorEnz 2.4.99.13
PRIAM enzyme-specific profiles Link: PRIAM 2.4.99.13
IntEnz Enzyme Link: IntEnz 2.4.99.13
MEDLINE Enzyme Link: MEDLINE 2.4.99.13
MSA:

2.4.99.13;

Phylogenetic Tree:

2.4.99.13;

Uniprot:
M-CSA:
RHEA:28062 alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate = alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3])(-[*:4])-[O;H0;+0:5]-[*:6].[*:7]-[OH;+0:8]>>[*:7]-[O;H0;+0:8]-[C;H0;+0:2](-[*:1])(-[*:3])-[*:4].[*:6]-[OH;+0:5]
Reaction
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References

TitleAuthorsDatePubMed ID
Molecular cloning, sequence analysis, and functional characterization of the lipopolysaccharide biosynthetic gene kdtA encoding 3-deoxy-alpha-D-manno-octulosonic acid transferase of Chlamydia pneumoniae strain TW-183.Löbau S, Mamat U, Brabetz W, Brade H1995 Nov8748024
Biosynthesis of endotoxins. Purification and catalytic properties of 3-deoxy-D-manno-octulosonic acid transferase from Escherichia coli.Belunis CJ, Raetz CR1992 May 151577828
A novel 3-deoxy-D-manno-octulosonic acid transferase from Chlamydia trachomatis required for expression of the genus-specific epitope.Belunis CJ, Mdluli KE, Raetz CR, Nano FE1992 Sep 151382060
Comparative analyses of secondary gene products of 3-deoxy-D-manno-oct-2-ulosonic acid transferases from Chlamydiaceae in Escherichia coli K-12.Brabetz W, Lindner B, Brade H2000 Sep10951204