EC Tree |
2. Transferases |
2.5 Transferring alkyl or aryl groups, other than methyl groups |
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date) |
ID: | 2.5.1.146 |
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Description: | 3-geranyl-3-((Z)-2-isocyanoethenyl)indole synthase. |
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 2.5.1.146 |
BRENDA Enzyme Link: | BRENDA 2.5.1.146 |
KEGG Enzyme Link: | KEGG2.5.1.146 |
BioCyc Enzyme Link: | BioCyc 2.5.1.146 |
ExPASy Enzyme Link: | ExPASy2.5.1.146 |
EC2PDB Enzyme Link: | EC2PDB 2.5.1.146 |
ExplorEnz Enzyme Link: | ExplorEnz 2.5.1.146 |
PRIAM enzyme-specific profiles Link: | PRIAM 2.5.1.146 |
IntEnz Enzyme Link: | IntEnz 2.5.1.146 |
MEDLINE Enzyme Link: | MEDLINE 2.5.1.146 |
MSA: | |
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Phylogenetic Tree: | |
Uniprot: | |
M-CSA: |
RHEA:17349 | (2E)-geranyl diphosphate + 3-[(Z)-2-isocyanoethenyl]-1H-indole = 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole + diphosphate |
RULE(radius=1) | [*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[*:5]-[c;H0;+0:6]1:[*:7]:[*:8]:[nH;+0:9]:[cH;+0:10]:1>>[*:1]-[CH2;+0:2]-[C;H0;+0:6]1(-[*:5])-[*:7]:[*:8]-[N;H0;+0:9]=[CH;+0:10]-1.[*:4]-[OH;+0:3] |
Reaction | ![]() |
Core-to-Core |
Title | Authors | Date | PubMed ID |
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Decoding cyclase-dependent assembly of hapalindole and fischerindole alkaloids. | Li S, Lowell AN, Newmister SA, Yu F, Williams RM, Sherman DH | 2017 May | 28288107 |