EC number:2.6.1.87
| ID: | 2.6.1.87 |
|---|---|
| Description: | UDP-4-amino-4-deoxy-L-arabinose aminotransferase. |
| Alternative Name: |
UDP-L-Ara4N transaminase. UDP-Ara4O aminotransferase. UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase. UDP-4-amino-4-deoxy-L-arabinose aminomutase. UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase. |
| Cath: | 3.40.640.10; 3.90.1150.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.6.1.87 |
| BRENDA Enzyme Link: | BRENDA 2.6.1.87 |
| KEGG Enzyme Link: | KEGG2.6.1.87 |
| BioCyc Enzyme Link: | BioCyc 2.6.1.87 |
| ExPASy Enzyme Link: | ExPASy2.6.1.87 |
| EC2PDB Enzyme Link: | EC2PDB 2.6.1.87 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.6.1.87 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.6.1.87 |
| IntEnz Enzyme Link: | IntEnz 2.6.1.87 |
| MEDLINE Enzyme Link: | MEDLINE 2.6.1.87 |
| RHEA:24710 | 2-oxoglutarate + UDP-4-amino-4-deoxy-beta-L-arabinose = L-glutamate + UDP-beta-L-threo-pentopyranos-4-ulose |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:5]-[CH;+0:6](-[*:7])-[NH2;+0:8]>>[*:5]-[C;H0;+0:6](-[*:7])=[O;H0;+0:4].[*:1]-[CH;+0:2](-[*:3])-[NH2;+0:8] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Structural basis for substrate specificity in ArnB. A key enzyme in the polymyxin resistance pathway of Gram-negative bacteria. | Lee M, Sousa MC | 2014 Feb 4 | 24460375 |
| Origin of lipid A species modified with 4-amino-4-deoxy-L-arabinose in polymyxin-resistant mutants of Escherichia coli. An aminotransferase (ArnB) that generates UDP-4-deoxyl-L-arabinose. | Breazeale SD, Ribeiro AA, Raetz CR | 2003 Jul 4 | 12704196 |
| Structural studies of Salmonella typhimurium ArnB (PmrH) aminotransferase: a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. | Noland BW, Newman JM, Hendle J, Badger J, Christopher JA, Tresser J, Buchanan MD, Wright TA, Rutter ME, Sanderson WE, Müller-Dieckmann HJ, Gajiwala KS, Buchanan SG | 2002 Nov | 12429098 |