Enzyme

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EC Tree
     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.1 Phosphotransferases with an alcohol group as acceptor
ID:2.7.1.170
Description:Anhydro-N-acetylmuramic acid kinase.
Alternative Name: AnhMurNAc kinase.
Cath: 1.10.8.10; 1.10.8.1080; 3.30.420.40; 3.40.50.10490;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.1.170
BRENDA Enzyme Link: BRENDA 2.7.1.170
KEGG Enzyme Link: KEGG2.7.1.170
BioCyc Enzyme Link: BioCyc 2.7.1.170
ExPASy Enzyme Link: ExPASy2.7.1.170
EC2PDB Enzyme Link: EC2PDB 2.7.1.170
ExplorEnz Enzyme Link: ExplorEnz 2.7.1.170
PRIAM enzyme-specific profiles Link: PRIAM 2.7.1.170
IntEnz Enzyme Link: IntEnz 2.7.1.170
MEDLINE Enzyme Link: MEDLINE 2.7.1.170
MSA:

2.7.1.170;

Phylogenetic Tree:

2.7.1.170;

Uniprot:
M-CSA:
RHEA:24952 1,6-anhydro-N-acetyl-beta-muramate + ATP + H2O = ADP + H(+) + N-acetyl-D-muramate 6-phosphate
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:4]-[*:5].[*:6]=[P;H0;+0:7](-[*:8])(-[*:9])-[O;H0;+0:10]-[*:11].[OH2;+0:12]>>([*:1]-[CH;+0:2](-[*:3])-[OH;+0:12].[*:6]=[P;H0;+0:7](-[*:8])(-[*:9])-[O;H0;+0:4]-[*:5]).[*:11]-[OH;+0:10]
Reaction
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References

TitleAuthorsDatePubMed ID
Molecular basis of 1,6-anhydro bond cleavage and phosphoryl transfer by Pseudomonas aeruginosa 1,6-anhydro-N-acetylmuramic acid kinase.Bacik JP, Whitworth GE, Stubbs KA, Yadav AK, Martin DR, Bailey-Elkin BA, Vocadlo DJ, Mark BL2011 Apr 821288904
MurQ Etherase is required by Escherichia coli in order to metabolize anhydro-N-acetylmuramic acid obtained either from the environment or from its own cell wall.Uehara T, Suefuji K, Jaeger T, Mayer C, Park JT2006 Feb16452451
Recycling of the anhydro-N-acetylmuramic acid derived from cell wall murein involves a two-step conversion to N-acetylglucosamine-phosphate.Uehara T, Suefuji K, Valbuena N, Meehan B, Donegan M, Park JT2005 Jun15901686