EC number:2.7.7.19

Enzyme

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     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.7 Nucleotidyltransferases
ID:2.7.7.19
Description:Polynucleotide adenylyltransferase.
Alternative Name: RNA adenylating enzyme.
Poly(A) polymerase.
NTP polymerase.
Cath: 1.10.10.10; 1.10.10.1950; 1.10.10.60; 1.10.132.30; 1.10.1320.10; 1.10.1410.10; 1.10.150.20; 1.10.150.390; 1.10.150.820; 1.10.1790.20;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.7.19
BRENDA Enzyme Link: BRENDA 2.7.7.19
KEGG Enzyme Link: KEGG2.7.7.19
BioCyc Enzyme Link: BioCyc 2.7.7.19
ExPASy Enzyme Link: ExPASy2.7.7.19
EC2PDB Enzyme Link: EC2PDB 2.7.7.19
ExplorEnz Enzyme Link: ExplorEnz 2.7.7.19
PRIAM enzyme-specific profiles Link: PRIAM 2.7.7.19
IntEnz Enzyme Link: IntEnz 2.7.7.19
MEDLINE Enzyme Link: MEDLINE 2.7.7.19

EC number:2.7.7.19

MSA:

2.7.7.19;
Phylogenetic Tree:

2.7.7.19;
Uniprot:
M-CSA:
RHEA:11332 ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
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References

TitleAuthorsDatePubMed ID
The terminal nucleotidyltransferases of calf thymus nuclei.Gottesman ME, Canellakis ES1966 Oct 104288534
Studies on the incorporation of deoxyribonucleic acid.KRAKOW JS, COUTSOGEORGOPOULOS C, CANELLAKIS ES1962 May 1414459258
Ribonucleic acid-dependent ribonucleotide incorporation. I. Purification and properties of the enzyme.AUGUST JT, ORTIZ PJ, HURWITZ J1962 Dec13965521
Polynucleotide biosynthesis: formation of a sequence of adenylate units from adenosine triphosphate by an enzyme from thymus nuclei.EDMONDS M, ABRAMS R1960 Apr13819354