EC number:2.7.7.69

Enzyme

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     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.7 Nucleotidyltransferases
ID:2.7.7.69
Description:GDP-L-galactose phosphorylase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.7.69
BRENDA Enzyme Link: BRENDA 2.7.7.69
KEGG Enzyme Link: KEGG2.7.7.69
BioCyc Enzyme Link: BioCyc 2.7.7.69
ExPASy Enzyme Link: ExPASy2.7.7.69
EC2PDB Enzyme Link: EC2PDB 2.7.7.69
ExplorEnz Enzyme Link: ExplorEnz 2.7.7.69
PRIAM enzyme-specific profiles Link: PRIAM 2.7.7.69
IntEnz Enzyme Link: IntEnz 2.7.7.69
MEDLINE Enzyme Link: MEDLINE 2.7.7.69

EC number:2.7.7.69

MSA:

2.7.7.69;
Phylogenetic Tree:

2.7.7.69;
Uniprot:
M-CSA:
RHEA:27698 GDP-beta-L-galactose + phosphate = beta-L-galactose 1-phosphate + GDP + H(+)
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]>>[*:4]-[CH;+0:3](-[*:5])-[O;H0;+0:7]-[*:6].[*:1]-[OH;+0:2]
Reaction
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References

TitleAuthorsDatePubMed ID
An expression analysis of the ascorbate biosynthesis enzyme VTC2.Müller-Moulé P2008 Sep18516687
A second GDP-L-galactose phosphorylase in arabidopsis en route to vitamin C. Covalent intermediate and substrate requirements for the conserved reaction.Linster CL, Adler LN, Webb K, Christensen KC, Brenner C, Clarke SG2008 Jul 418463094
Two genes in Arabidopsis thaliana encoding GDP-L-galactose phosphorylase are required for ascorbate biosynthesis and seedling viability.Dowdle J, Ishikawa T, Gatzek S, Rolinski S, Smirnoff N2007 Nov17877701
Arabidopsis VTC2 encodes a GDP-L-galactose phosphorylase, the last unknown enzyme in the Smirnoff-Wheeler pathway to ascorbic acid in plants.Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG2007 Jun 2917462988