EC number:2.7.7.70

Enzyme

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     2. Transferases
        2.7 Transferring phosphorus-containing groups
            2.7.7 Nucleotidyltransferases
ID:2.7.7.70
Description:D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase.
Alternative Name: D-glycero-D-manno-heptose-1-beta-phosphate adenylyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.7.7.70
BRENDA Enzyme Link: BRENDA 2.7.7.70
KEGG Enzyme Link: KEGG2.7.7.70
BioCyc Enzyme Link: BioCyc 2.7.7.70
ExPASy Enzyme Link: ExPASy2.7.7.70
EC2PDB Enzyme Link: EC2PDB 2.7.7.70
ExplorEnz Enzyme Link: ExplorEnz 2.7.7.70
PRIAM enzyme-specific profiles Link: PRIAM 2.7.7.70
IntEnz Enzyme Link: IntEnz 2.7.7.70
MEDLINE Enzyme Link: MEDLINE 2.7.7.70

EC number:2.7.7.70

MSA:

2.7.7.70;
Phylogenetic Tree:

2.7.7.70;
Uniprot:
M-CSA:
RHEA:27465 ATP + D-glycero-beta-D-manno-heptose 1-phosphate + H(+) = ADP-D-glycero-beta-D-manno-heptose + diphosphate
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:7]-[*:8].[H+;H0:9]>>[*:8]-[OH;+0:7].[*:3]=[P;H0;+0:4](-[*:5])(-[*:6])-[O;H0;+0:2]-[*:1]
Reaction
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References

TitleAuthorsDatePubMed ID
Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli.Kneidinger B, Marolda C, Graninger M, Zamyatina A, McArthur F, Kosma P, Valvano MA, Messner P2002 Jan11751812
The rfaE gene from Escherichia coli encodes a bifunctional protein involved in biosynthesis of the lipopolysaccharide core precursor ADP-L-glycero-D-manno-heptose.Valvano MA, Marolda CL, Bittner M, Glaskin-Clay M, Simon TL, Klena JD2000 Jan10629197