EC number:2.7.7.83
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.7 Transferring phosphorus-containing groups |
| 2.7.7 Nucleotidyltransferases |
| ID: | 2.7.7.83 |
|---|---|
| Description: | UDP-N-acetylgalactosamine diphosphorylase. |
| Cath: | 3.90.550.10; 2.160.10.10; 3.40.1630.20; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.7.7.83 |
| BRENDA Enzyme Link: | BRENDA 2.7.7.83 |
| KEGG Enzyme Link: | KEGG2.7.7.83 |
| BioCyc Enzyme Link: | BioCyc 2.7.7.83 |
| ExPASy Enzyme Link: | ExPASy2.7.7.83 |
| EC2PDB Enzyme Link: | EC2PDB 2.7.7.83 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.7.7.83 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.7.7.83 |
| IntEnz Enzyme Link: | IntEnz 2.7.7.83 |
| MEDLINE Enzyme Link: | MEDLINE 2.7.7.83 |
| RHEA:34363 | H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-galactosamine |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]-[P;H0;+0:4](=[*:5])(-[*:6])-[O;H0;+0:7]-[*:8].[H+;H0:9]>>[*:8]-[OH;+0:7].[*:3]-[P;H0;+0:4](=[*:5])(-[*:6])-[O;H0;+0:2]-[*:1] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Acetyltransfer precedes uridylyltransfer in the formation of UDP-N-acetylglucosamine in separable active sites of the bifunctional GlmU protein of Escherichia coli. | Gehring AM, Lees WJ, Mindiola DJ, Walsh CT, Brown ED | 1996 Jan 16 | 8555230 |
| Crystal structures of two human pyrophosphorylase isoforms in complexes with UDPGlc(Gal)NAc: role of the alternatively spliced insert in the enzyme oligomeric assembly and active site architecture. | Peneff C, Ferrari P, Charrier V, Taburet Y, Monnier C, Zamboni V, Winter J, Harnois M, Fassy F, Bourne Y | 2001 Nov 15 | 11707391 |
| A 17-amino acid insert changes UDP-N-acetylhexosamine pyrophosphorylase specificity from UDP-GalNAc to UDP-GlcNAc. | Wang-Gillam A, Pastuszak I, Elbein AD | 1998 Oct 16 | 9765219 |
| Identification and characterization of a strict and a promiscuous N-acetylglucosamine-1-P uridylyltransferase in Arabidopsis. | Yang T, Echols M, Martin A, Bar-Peled M | 2010 Sep 1 | 20557289 |