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2. Transferases

2.7 Transferring phosphorus-containing groups

2.7.8 Transferases for other substituted phosphate groups

ID:	2.7.8.26
Description:	Adenosylcobinamide-GDP ribazoletransferase.
Alternative Name:	Cobalamin-5'-phosphate synthase. Cobalamin synthase. Cobalamin (5'-phosphate) synthase.
Cath:	3.90.550.10; 3.40.50.300;

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UniProtKB Enzyme Link:	UniProtKB 2.7.8.26
BRENDA Enzyme Link:	BRENDA 2.7.8.26
KEGG Enzyme Link:	KEGG2.7.8.26
BioCyc Enzyme Link:	BioCyc 2.7.8.26
ExPASy Enzyme Link:	ExPASy2.7.8.26
EC2PDB Enzyme Link:	EC2PDB 2.7.8.26
ExplorEnz Enzyme Link:	ExplorEnz 2.7.8.26
PRIAM enzyme-specific profiles Link:	PRIAM 2.7.8.26
IntEnz Enzyme Link:	IntEnz 2.7.8.26
MEDLINE Enzyme Link:	MEDLINE 2.7.8.26

RHEA:23560	adenosylcob(III)inamide-GDP + alpha-ribazole 5'-phosphate = adenosylcob(III)alamin 5'-phosphate + GMP + H(+)
RULE(radius=1)	([:1]-[Co-2;H0:2](-[:3])(-[:4])(-[:5])-[:6].[:7]-[O;H0;+0:8]-[P;H0;+0:9](=[:10])(-[:11])-[:12]).([:13]-[OH;+0:14].[:15]:[n;H0;+0:16]:[:17])>>([:13]-[O;H0;+0:14]-[P;H0;+0:9](=[:10])(-[:11])-[:12].[:15]:[n+;H0:16](:[:17])-[Co-3;H0:2](-[:1])(-[:3])(-[:4])(-[:5])-[:6]).[:7]-[OH;+0:8]
Reaction
Core-to-Core	More
Core-to-Core	More
Core-to-Core	More

Title	Authors	Date	PubMed ID
In vitro synthesis of the nucleotide loop of cobalamin by Salmonella typhimurium enzymes.	Maggio-Hall LA, Escalante-Semerena JC	1999 Oct 12	10518530
The biosynthesis of adenosylcobalamin (vitamin B12).	Warren MJ, Raux E, Schubert HL, Escalante-Semerena JC	2002 Aug	12195810
Genetic analysis, nucleotide sequence, and products of two Pseudomonas denitrificans cob genes encoding nicotinate-nucleotide: dimethylbenzimidazole phosphoribosyltransferase and cobalamin (5'-phosphate) synthase.	Cameron B, Blanche F, Rouyez MC, Bisch D, Famechon A, Couder M, Cauchois L, Thibaut D, Debussche L, Crouzet J	1991 Oct	1917841

RHEA:16049	adenosylcob(III)inamide-GDP + alpha-ribazole = adenosylcob(III)alamin + GMP + H(+)
RULE(radius=1)	([:1]-[Co-2;H0:2](-[:3])(-[:4])(-[:5])-[:6].[:7]-[O;H0;+0:8]-[P;H0;+0:9](=[:10])(-[:11])-[:12]).([:13]-[OH;+0:14].[:15]:[n;H0;+0:16]:[:17])>>([:13]-[O;H0;+0:14]-[P;H0;+0:9](=[:10])(-[:11])-[:12].[:15]:[n+;H0:16](:[:17])-[Co-3;H0:2](-[:1])(-[:3])(-[:4])(-[:5])-[:6]).[:7]-[OH;+0:8]
Reaction
Core-to-Core	No scaffolds atoms were exchanged as a result of the reaction

Title	Authors	Date	PubMed ID
In vitro synthesis of the nucleotide loop of cobalamin by Salmonella typhimurium enzymes.	Maggio-Hall LA, Escalante-Semerena JC	1999 Oct 12	10518530
The biosynthesis of adenosylcobalamin (vitamin B12).	Warren MJ, Raux E, Schubert HL, Escalante-Semerena JC	2002 Aug	12195810