EC number:2.8.1.13
Enzyme
Download| EC Tree |
| 2. Transferases |
| 2.8 Transferring sulfur-containing groups |
| 2.8.1 Sulfurtransferases |
| ID: | 2.8.1.13 |
|---|---|
| Description: | tRNA-uridine 2-sulfurtransferase. |
| Cath: | 3.40.50.620; 2.30.30.280; 2.40.30.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.8.1.13 |
| BRENDA Enzyme Link: | BRENDA 2.8.1.13 |
| KEGG Enzyme Link: | KEGG2.8.1.13 |
| BioCyc Enzyme Link: | BioCyc 2.8.1.13 |
| ExPASy Enzyme Link: | ExPASy2.8.1.13 |
| EC2PDB Enzyme Link: | EC2PDB 2.8.1.13 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.8.1.13 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.8.1.13 |
| IntEnz Enzyme Link: | IntEnz 2.8.1.13 |
| MEDLINE Enzyme Link: | MEDLINE 2.8.1.13 |
| RHEA:47032 | AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein] |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[P;H0;+0:3](-[*:4])(=[*:5])-[*:6].[*:7]-[S;H0;+0:8]-[SH;+0:9].[*:10]:[c;H0;+0:11](:[*:12])=[O;H0;+0:13]>>[*:1]-[OH;+0:2].[*:4]-[P;H0;+0:3](=[*:5])(-[*:6])-[OH;+0:13].[*:7]-[SH;+0:8].[*:10]:[c;H0;+0:11](:[*:12])=[S;H0;+0:9] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Mechanistic insights into sulfur relay by multiple sulfur mediators involved in thiouridine biosynthesis at tRNA wobble positions. | Ikeuchi Y, Shigi N, Kato J, Nishimura A, Suzuki T | 2006 Jan 6 | 16387657 |
| MnmA and IscS are required for in vitro 2-thiouridine biosynthesis in Escherichia coli. | Kambampati R, Lauhon CT | 2003 Feb 4 | 12549933 |