Enzyme

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EC Tree
     3. Hydrolases
        3.1 Acting on ester bonds
            3.1.4 Phosphoric-diester hydrolases
ID:3.1.4.52
Description:Cyclic-guanylate-specific phosphodiesterase.
Alternative Name: Phosphodiesterase A1.
PDEA1.
C-di-GMP-specific phosphodiesterase.
Cath: 1.10.3210.10; 3.20.20.450; 3.30.450.20; 3.30.70.270;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.1.4.52
BRENDA Enzyme Link: BRENDA 3.1.4.52
KEGG Enzyme Link: KEGG3.1.4.52
BioCyc Enzyme Link: BioCyc 3.1.4.52
ExPASy Enzyme Link: ExPASy3.1.4.52
EC2PDB Enzyme Link: EC2PDB 3.1.4.52
ExplorEnz Enzyme Link: ExplorEnz 3.1.4.52
PRIAM enzyme-specific profiles Link: PRIAM 3.1.4.52
IntEnz Enzyme Link: IntEnz 3.1.4.52
MEDLINE Enzyme Link: MEDLINE 3.1.4.52
MSA:

3.1.4.52;

Phylogenetic Tree:

3.1.4.52;

Uniprot:
M-CSA:
RHEA:24902 cyclic di-3',5'-guanylate + H2O = 5'-phosphoguanylyl(3'->5')guanosine + H(+)
RULE(radius=1) ([*:1]-[OH;+0:2].[*:3]-[P;H0;+0:4](=[*:5])(-[*:6])-[OH;+0:7]).[H+;H0:8]>>[*:3]-[P;H0;+0:4](=[*:5])(-[*:6])-[O;H0;+0:2]-[*:1].[OH2;+0:7]
Reaction
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