| EC Tree |
| 3. Hydrolases |
| 3.2 Glycosylases |
| 3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds |
| ID: | 3.2.1.107 |
|---|---|
| Description: | Protein-glucosylgalactosylhydroxylysine glucosidase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 3.2.1.107 |
| BRENDA Enzyme Link: | BRENDA 3.2.1.107 |
| KEGG Enzyme Link: | KEGG3.2.1.107 |
| BioCyc Enzyme Link: | BioCyc 3.2.1.107 |
| ExPASy Enzyme Link: | ExPASy3.2.1.107 |
| EC2PDB Enzyme Link: | EC2PDB 3.2.1.107 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.2.1.107 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.2.1.107 |
| IntEnz Enzyme Link: | IntEnz 3.2.1.107 |
| MEDLINE Enzyme Link: | MEDLINE 3.2.1.107 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:11068 | (5R)-5-O-[alpha-D-glucosyl-(1->2)-beta-D-galactosyl]-5-hydroxy-L-lysyl-[procollagen] + H2O = (5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[procollagen] + D-glucose |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[OH2;+0:6]>>[*:4]-[CH;+0:3](-[*:5])-[OH;+0:6].[*:1]-[OH;+0:2] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Enzymatic hydrolysis of disaccharide unit of collagen. Isolation of 2-O-alpha-D-glucopyranosyl-O-beta-D-galactopyranosyl-hydroxylysine glucohydrolase from rat spleens. | Hamazaki H, Hotta K | 1980 Oct | 7460918 |
| Purification and characterization of an alpha-glucosidase specific for hydroxylysine-linked disaccharide of collagen. | Hamazaki H, Hotta K | 1979 Oct 10 | 385589 |
| Catalytic site of human protein-glucosylgalactosylhydroxylysine glucosidase: Three crucial carboxyl residues were determined by cloning and site-directed mutagenesis. | Hamazaki H, Hamazaki MH | 2016 Jan 15 | 26682924 |
| Studies on the catabolism of the hydroxylysine-linked disaccharide units of basement membranes and collagens. Isolation and characterization of a rat kidney alpha-glucosidase of high specificity. | Sternberg M, Spiro RG | 1979 Oct 25 | 385599 |