Enzyme

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     3. Hydrolases
        3.2 Glycosylases
            3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
ID:3.2.1.108
Description:Lactase.
Prosite: PDOC00495;
PDB:
PDBScop
Cath: 3.20.20.80; 3.40.50.880; 2.102.20.10; 2.60.120.260; 2.60.220.20; 2.60.390.10; 2.60.40.10; 2.60.40.1180; 2.70.98.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.2.1.108
BRENDA Enzyme Link: BRENDA 3.2.1.108
KEGG Enzyme Link: KEGG3.2.1.108
BioCyc Enzyme Link: BioCyc 3.2.1.108
ExPASy Enzyme Link: ExPASy3.2.1.108
EC2PDB Enzyme Link: EC2PDB 3.2.1.108
ExplorEnz Enzyme Link: ExplorEnz 3.2.1.108
PRIAM enzyme-specific profiles Link: PRIAM 3.2.1.108
IntEnz Enzyme Link: IntEnz 3.2.1.108
MEDLINE Enzyme Link: MEDLINE 3.2.1.108
MSA:

3.2.1.108;

Phylogenetic Tree:

3.2.1.108;

Uniprot:
M-CSA:
RHEA:10076 H2O + lactose = D-galactose + D-glucose
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:4]-[*:5].[OH2;+0:6]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:6].[*:5]-[OH;+0:4]
Reaction
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References

TitleAuthorsDatePubMed ID
Further characterization of intestinal lactase/phlorizin hydrolase.Skovbjerg H, Norén O, Sjöström H, Danielsen EM, Enevoldsen BS1982 Sep 226814489
Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase phlorizin hydrolase.Day AJ, Cañada FJ, Díaz JC, Kroon PA, Mclauchlan R, Faulds CB, Plumb GW, Morgan MR, Williamson G2000 Feb 2510692580