Enzyme

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EC Tree
     3. Hydrolases
        3.2 Glycosylases
            3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
ID:3.2.1.180
Description:Unsaturated chondroitin disaccharide hydrolase.
Alternative Name: Unsaturated glucuronyl hydrolase.
Cath: 1.50.10.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.2.1.180
BRENDA Enzyme Link: BRENDA 3.2.1.180
KEGG Enzyme Link: KEGG3.2.1.180
BioCyc Enzyme Link: BioCyc 3.2.1.180
ExPASy Enzyme Link: ExPASy3.2.1.180
EC2PDB Enzyme Link: EC2PDB 3.2.1.180
ExplorEnz Enzyme Link: ExplorEnz 3.2.1.180
PRIAM enzyme-specific profiles Link: PRIAM 3.2.1.180
IntEnz Enzyme Link: IntEnz 3.2.1.180
MEDLINE Enzyme Link: MEDLINE 3.2.1.180
MSA:

3.2.1.180;

Phylogenetic Tree:

3.2.1.180;

Uniprot:
M-CSA:
RHEA:31647 beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate
RULE(radius=1) [*:1]-[C;H0;+0:2]1=[CH;+0:3]-[*:4]-[*:5]-[CH;+0:6](-[O;H0;+0:7]-[*:8])-[O;H0;+0:9]-1.[OH2;+0:10]>>[*:1]-[C;H0;+0:2](=[O;H0;+0:9])-[CH2;+0:3]-[*:4]-[*:5]-[CH;+0:6]=[O;H0;+0:10].[*:8]-[OH;+0:7]
Reaction
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References

TitleAuthorsDatePubMed ID
Structural determinants in streptococcal unsaturated glucuronyl hydrolase for recognition of glycosaminoglycan sulfate groups.Nakamichi Y, Maruyama Y, Mikami B, Hashimoto W, Murata K2011 Feb 2521147778
Substrate specificity of streptococcal unsaturated glucuronyl hydrolases for sulfated glycosaminoglycan.Maruyama Y, Nakamichi Y, Itoh T, Mikami B, Hashimoto W, Murata K2009 Jul 319416976