| EC Tree |
| 3. Hydrolases |
| 3.2 Glycosylases |
| 3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds |
| ID: | 3.2.1.180 |
|---|---|
| Description: | Unsaturated chondroitin disaccharide hydrolase. |
| Alternative Name: |
Unsaturated glucuronyl hydrolase. |
| Cath: | 1.50.10.10; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 3.2.1.180 |
| BRENDA Enzyme Link: | BRENDA 3.2.1.180 |
| KEGG Enzyme Link: | KEGG3.2.1.180 |
| BioCyc Enzyme Link: | BioCyc 3.2.1.180 |
| ExPASy Enzyme Link: | ExPASy3.2.1.180 |
| EC2PDB Enzyme Link: | EC2PDB 3.2.1.180 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.2.1.180 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.2.1.180 |
| IntEnz Enzyme Link: | IntEnz 3.2.1.180 |
| MEDLINE Enzyme Link: | MEDLINE 3.2.1.180 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:31647 | beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[CH;+0:3]-[*:4]-[*:5]-[CH;+0:6](-[O;H0;+0:7]-[*:8])-[O;H0;+0:9]-1.[OH2;+0:10]>>[*:1]-[C;H0;+0:2](=[O;H0;+0:9])-[CH2;+0:3]-[*:4]-[*:5]-[CH;+0:6]=[O;H0;+0:10].[*:8]-[OH;+0:7] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Structural determinants in streptococcal unsaturated glucuronyl hydrolase for recognition of glycosaminoglycan sulfate groups. | Nakamichi Y, Maruyama Y, Mikami B, Hashimoto W, Murata K | 2011 Feb 25 | 21147778 |
| Substrate specificity of streptococcal unsaturated glucuronyl hydrolases for sulfated glycosaminoglycan. | Maruyama Y, Nakamichi Y, Itoh T, Mikami B, Hashimoto W, Murata K | 2009 Jul 3 | 19416976 |