EC number:3.2.2.9
| ID: | 3.2.2.9 |
|---|---|
| Description: | Adenosylhomocysteine nucleosidase. |
| Alternative Name: |
S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase. S-adenosylhomocysteine nucleosidase. S-adenosylhomocysteine hydrolase. AdoHcy/MTA nucleosidase. 5'-methyladenosine nucleosidase. |
| Cath: | 3.40.50.1580; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.2.2.9 |
| BRENDA Enzyme Link: | BRENDA 3.2.2.9 |
| KEGG Enzyme Link: | KEGG3.2.2.9 |
| BioCyc Enzyme Link: | BioCyc 3.2.2.9 |
| ExPASy Enzyme Link: | ExPASy3.2.2.9 |
| EC2PDB Enzyme Link: | EC2PDB 3.2.2.9 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.2.2.9 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.2.2.9 |
| IntEnz Enzyme Link: | IntEnz 3.2.2.9 |
| MEDLINE Enzyme Link: | MEDLINE 3.2.2.9 |
| RHEA:29859 | 5'-deoxyadenosine + H2O = 5-deoxy-D-ribose + adenine |
| RULE(radius=1) | [*:1]:[n;H0;+0:2](:[*:3])-[CH;+0:4]1-[*:5]-[*:6]-[CH;+0:7](-[*:8])-[O;H0;+0:9]-1.[OH2;+0:10]>>[*:8]-[CH;+0:7](-[OH;+0:10])-[*:6]-[*:5]-[CH;+0:4]=[O;H0;+0:9].[*:1]:[nH;+0:2]:[*:3] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Biotin synthase exhibits burst kinetics and multiple turnovers in the absence of inhibition by products and product-related biomolecules. | Farrar CE, Siu KK, Howell PL, Jarrett JT | 2010 Nov 23 | 20961145 |
| RHEA:17805 | H2O + S-adenosyl-L-homocysteine = adenine + S-(5-deoxy-D-ribos-5-yl)-L-homocysteine |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[n;H0;+0:4](:[*:5]):[*:6].[OH2;+0:7]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:7].[*:5]:[nH;+0:4]:[*:6] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
| RHEA:13617 | H2O + S-methyl-5'-thioadenosine = adenine + S-methyl-5-thio-D-ribose |
| RULE(radius=1) | [*:1]:[n;H0;+0:2](:[*:3])-[CH;+0:4]1-[*:5]-[*:6]-[CH;+0:7](-[*:8])-[O;H0;+0:9]-1.[OH2;+0:10]>>[*:8]-[CH;+0:7](-[OH;+0:10])-[*:6]-[*:5]-[CH;+0:4]=[O;H0;+0:9].[*:1]:[nH;+0:2]:[*:3] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| 5'-Methylthioadenosine nucleosidase. Purification and characterization of the enzyme from Lupinus luteus seeds. | Guranowski AB, Chiang PK, Cantoni GL | 1981 Feb | 6783408 |