EC number:3.6.1.13

Enzyme

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     3. Hydrolases
        3.6 Acting on acid anhydrides
            3.6.1 In phosphorus-containing anhydrides
ID:3.6.1.13
Description:ADP-ribose diphosphatase.
Alternative Name: ADPR-PPase.
ADP-ribose ribophosphohydrolase.
ADP-ribose pyrophosphatase.
ADP-ribose phosphohydrolase.
Adenosine diphosphoribose pyrophosphatase.
Cath: 3.60.21.10; 3.90.79.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.6.1.13
BRENDA Enzyme Link: BRENDA 3.6.1.13
KEGG Enzyme Link: KEGG3.6.1.13
BioCyc Enzyme Link: BioCyc 3.6.1.13
ExPASy Enzyme Link: ExPASy3.6.1.13
EC2PDB Enzyme Link: EC2PDB 3.6.1.13
ExplorEnz Enzyme Link: ExplorEnz 3.6.1.13
PRIAM enzyme-specific profiles Link: PRIAM 3.6.1.13
IntEnz Enzyme Link: IntEnz 3.6.1.13
MEDLINE Enzyme Link: MEDLINE 3.6.1.13

EC number:3.6.1.13

MSA:

3.6.1.13;
Phylogenetic Tree:

3.6.1.13;
Uniprot:
M-CSA:
RHEA:10412 ADP-D-ribose + H2O = AMP + D-ribose 5-phosphate + 2 H(+)
RULE(radius=1) [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7]
Reaction
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References

TitleAuthorsDatePubMed ID
Rat liver nucleoside diphosphosugar or diphosphoalcohol pyrophosphatases different from nucleotide pyrophosphatase or phosphodiesterase I: substrate specificities of Mg(2+)-and/or Mn(2+)-dependent hydrolases acting on ADP-ribose.Canales J, Pinto RM, Costas MJ, Hernández MT, Miró A, Bernet D, Fernández A, Cameselle JC1995 Jan 197819284
Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase: a novel metallophosphoesterase family preferentially expressed in rodent immune cells.Canales J, Fernández A, Ribeiro JM, Cabezas A, Rodrigues JR, Cameselle JC, Costas MJ2008 Jul 118352857