EC number:3.6.1.61

Enzyme

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     3. Hydrolases
        3.6 Acting on acid anhydrides
            3.6.1 In phosphorus-containing anhydrides
ID:3.6.1.61
Description:Diadenosine hexaphosphate hydrolase (ATP-forming).
Cath: 3.90.79.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.6.1.61
BRENDA Enzyme Link: BRENDA 3.6.1.61
KEGG Enzyme Link: KEGG3.6.1.61
BioCyc Enzyme Link: BioCyc 3.6.1.61
ExPASy Enzyme Link: ExPASy3.6.1.61
EC2PDB Enzyme Link: EC2PDB 3.6.1.61
ExplorEnz Enzyme Link: ExplorEnz 3.6.1.61
PRIAM enzyme-specific profiles Link: PRIAM 3.6.1.61
IntEnz Enzyme Link: IntEnz 3.6.1.61
MEDLINE Enzyme Link: MEDLINE 3.6.1.61

EC number:3.6.1.61

MSA:

3.6.1.61;
Phylogenetic Tree:

3.6.1.61;
Uniprot:
M-CSA:
RHEA:32043 H2O + P(1),P(6)-bis(5'-adenosyl)hexaphosphate = 2 ATP + 2 H(+)
RULE(radius=1) [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
The Nudix hydrolase Ndx1 from Thermus thermophilus HB8 is a diadenosine hexaphosphate hydrolase with a novel activity.Iwai T, Kuramitsu S, Masui R2004 May 2115024014
RHEA:32039 H2O + P(1),P(4)-bis(5'-adenosyl)tetraphosphate = AMP + ATP + 2 H(+)
RULE(radius=1) [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
The Nudix hydrolase Ndx1 from Thermus thermophilus HB8 is a diadenosine hexaphosphate hydrolase with a novel activity.Iwai T, Kuramitsu S, Masui R2004 May 2115024014
RHEA:30527 H2O + P(1),P(5)-bis(5'-adenosyl)pentaphosphate = ADP + ATP + 2 H(+)
RULE(radius=1) [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
The Nudix hydrolase Ndx1 from Thermus thermophilus HB8 is a diadenosine hexaphosphate hydrolase with a novel activity.Iwai T, Kuramitsu S, Masui R2004 May 2115024014