EC number:4.1.1.100

Enzyme

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EC Tree
     4. Lyases
        4.1 Carbon-carbon lyases
            4.1.1 Carboxy-lyases
ID:4.1.1.100
Description:Prephenate decarboxylase.
Alternative Name: Non-aromatizing prephenate decarboxylase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.1.1.100
BRENDA Enzyme Link: BRENDA 4.1.1.100
KEGG Enzyme Link: KEGG4.1.1.100
BioCyc Enzyme Link: BioCyc 4.1.1.100
ExPASy Enzyme Link: ExPASy4.1.1.100
EC2PDB Enzyme Link: EC2PDB 4.1.1.100
ExplorEnz Enzyme Link: ExplorEnz 4.1.1.100
PRIAM enzyme-specific profiles Link: PRIAM 4.1.1.100
IntEnz Enzyme Link: IntEnz 4.1.1.100
MEDLINE Enzyme Link: MEDLINE 4.1.1.100

EC number:4.1.1.100

MSA:

4.1.1.100;
Phylogenetic Tree:

4.1.1.100;
Uniprot:
M-CSA:
RHEA:33499 H(+) + prephenate = 3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate + CO2
RULE(radius=1) [*:1]-[CH;+0:2]=[CH;+0:3]-[C;H0;+0:4](-[*:5])(-[*:6])-[C;H0;+0:7](=[*:8])-[OH;+0:9].[H+;H0:10]>>[*:1]-[CH2;+0:2]-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[*:6].[*:8]=[C;H0;+0:7]=[O;H0;+0:9]
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References

TitleAuthorsDatePubMed ID
Olefin isomerization regiochemistries during tandem action of BacA and BacB on prephenate in bacilysin biosynthesis.Parker JB, Walsh CT2012 Apr 1722483065
Prephenate decarboxylases: a new prephenate-utilizing enzyme family that performs nonaromatizing decarboxylation en route to diverse secondary metabolites.Mahlstedt S, Fielding EN, Moore BS, Walsh CT2010 Oct 2620863139
Investigation of anticapsin biosynthesis reveals a four-enzyme pathway to tetrahydrotyrosine in Bacillus subtilis.Mahlstedt SA, Walsh CT2010 Feb 920052993