EC number:4.1.1.48

Enzyme

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     4. Lyases
        4.1 Carbon-carbon lyases
            4.1.1 Carboxy-lyases
ID:4.1.1.48
Description:Indole-3-glycerol-phosphate synthase.
Alternative Name: Indoleglycerol phosphate synthetase.
Prosite: PDOC00536;
PDB:
PDBScop
5K7J 8030880; 8043259; 8030880; 8043259;
4IWW 8030880; 8043259; 8030880; 8043259;
4IX0 8030880; 8043259;
3TC6 8030880; 8043259;
2C3Z 8030880; 8043259;
 » show all
Cath: 3.20.20.70; 3.30.429.10; 3.40.1030.10; 3.40.50.880; 3.60.120.10; 1.20.970.10; 3.40.50.1100;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 4.1.1.48
BRENDA Enzyme Link: BRENDA 4.1.1.48
KEGG Enzyme Link: KEGG4.1.1.48
BioCyc Enzyme Link: BioCyc 4.1.1.48
ExPASy Enzyme Link: ExPASy4.1.1.48
EC2PDB Enzyme Link: EC2PDB 4.1.1.48
ExplorEnz Enzyme Link: ExplorEnz 4.1.1.48
PRIAM enzyme-specific profiles Link: PRIAM 4.1.1.48
IntEnz Enzyme Link: IntEnz 4.1.1.48
MEDLINE Enzyme Link: MEDLINE 4.1.1.48

EC number:4.1.1.48

MSA:

4.1.1.48;
Phylogenetic Tree:

4.1.1.48;
Uniprot:
M-CSA:
RHEA:23476 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O
RULE(radius=1) [*:1]-[C;H0;+0:2](=[O;H0;+0:3])-[CH2;+0:4]-[NH;+0:5]-[*:6]:[c;H0;+0:7](:[*:8])-[C;H0;+0:9](=[*:10])-[OH;+0:11].[H+;H0:12]>>[*:1]-[c;H0;+0:2]1:[cH;+0:4]:[nH;+0:5]:[*:6]:[c;H0;+0:7]:1:[*:8].[*:10]=[C;H0;+0:9]=[O;H0;+0:11].[OH2;+0:3]
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