EC number:4.1.3.27
| ID: | 4.1.3.27 | ||
|---|---|---|---|
| Description: | Anthranilate synthase. | ||
| Prosite: | PDOC00405; | ||
| PDB: |
|
||
| Cath: | 3.20.20.70; 3.30.429.10; 3.40.1030.10; 3.40.50.880; 3.60.120.10; 1.20.970.10; 3.40.50.1100; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 4.1.3.27 |
| BRENDA Enzyme Link: | BRENDA 4.1.3.27 |
| KEGG Enzyme Link: | KEGG4.1.3.27 |
| BioCyc Enzyme Link: | BioCyc 4.1.3.27 |
| ExPASy Enzyme Link: | ExPASy4.1.3.27 |
| EC2PDB Enzyme Link: | EC2PDB 4.1.3.27 |
| ExplorEnz Enzyme Link: | ExplorEnz 4.1.3.27 |
| PRIAM enzyme-specific profiles Link: | PRIAM 4.1.3.27 |
| IntEnz Enzyme Link: | IntEnz 4.1.3.27 |
| MEDLINE Enzyme Link: | MEDLINE 4.1.3.27 |
| RHEA:21732 | chorismate + L-glutamine = anthranilate + H(+) + L-glutamate + pyruvate |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[NH2;+0:4].[*:5]-[C;H0;+0:6]1=[CH;+0:7]-[CH;+0:8](-[O;H0;+0:9]-[C;H0;+0:10](-[*:11])=[CH2;+0:12])-[CH;+0:13](-[OH;+0:14])-[CH;+0:15]=[CH;+0:16]-1>>[*:11]-[C;H0;+0:10](-[CH3;+0:12])=[O;H0;+0:9].[*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:14].[*:5]-[c;H0;+0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:13]:[cH;+0:15]:[c;H0;+0:16]:1-[NH2;+0:4] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Anthranilate synthetase. Partial purification and some kinetic studies on the enzyme from Escherichia coli. | Baker TI, Crawford IP | 1966 Dec 10 | 5333199 |
| Anthranilate synthetase, an enzyme specified by the tryptophan operon of Escherichia coli: Comparative studies on the complex and the subunits. | Ito J, Yanofsky C | 1969 Feb | 4886290 |
| Anthranilate synthetase, an enzyme specified by the tryptophan operon of Escherichia coli: purification and characterization of component I. | Ito J, Cox EC, Yanofsky C | 1969 Feb | 4886289 |
| Anthranilate synthetase. Purification and properties of component I from Salmonella typhimurium. | Zalkin H, Kling D | 1968 Oct | 4878701 |
| The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end-product inhibitor, L-tryptophan. | Spraggon G, Kim C, Nguyen-Huu X, Yee MC, Yanofsky C, Mills SE | 2001 May 22 | 11371633 |