Enzyme

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EC Tree
     4. Lyases
        4.1 Carbon-carbon lyases
            4.1.3 Oxo-acid-lyases
ID:4.1.3.45
Description:3-hydroxybenzoate synthase.
Alternative Name: Chorismatase/3-hydroxybenzoate synthase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 4.1.3.45
BRENDA Enzyme Link: BRENDA 4.1.3.45
KEGG Enzyme Link: KEGG4.1.3.45
BioCyc Enzyme Link: BioCyc 4.1.3.45
ExPASy Enzyme Link: ExPASy4.1.3.45
EC2PDB Enzyme Link: EC2PDB 4.1.3.45
ExplorEnz Enzyme Link: ExplorEnz 4.1.3.45
PRIAM enzyme-specific profiles Link: PRIAM 4.1.3.45
IntEnz Enzyme Link: IntEnz 4.1.3.45
MEDLINE Enzyme Link: MEDLINE 4.1.3.45
MSA:

4.1.3.45;

Phylogenetic Tree:

4.1.3.45;

Uniprot:
M-CSA:
RHEA:38315 chorismate = 3-hydroxybenzoate + pyruvate
RULE(radius=1) [*:1]-[C;H0;+0:2]1=[CH;+0:3]-[CH;+0:4](-[O;H0;+0:5]-[C;H0;+0:6](-[*:7])=[CH2;+0:8])-[CH;+0:9](-[OH;+0:10])-[CH;+0:11]=[CH;+0:12]-1>>[*:7]-[C;H0;+0:6](-[CH3;+0:8])=[O;H0;+0:10].[*:1]-[c;H0;+0:2]1:[cH;+0:3]:[c;H0;+0:4](-[OH;+0:5]):[cH;+0:9]:[cH;+0:11]:[cH;+0:12]:1
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References

TitleAuthorsDatePubMed ID
Identification and characterization of the cuevaene A biosynthetic gene cluster in streptomyces sp. LZ35.Jiang Y, Wang H, Lu C, Ding Y, Li Y, Shen Y2013 Aug 1923824670
The diffusible factor synthase XanB2 is a bifunctional chorismatase that links the shikimate pathway to ubiquinone and xanthomonadins biosynthetic pathways.Zhou L, Wang JY, Wu J, Wang J, Poplawsky A, Lin S, Zhu B, Chang C, Zhou T, Zhang LH, He YW2013 Jan23113660
Biosynthesis of the immunosuppressants FK506, FK520, and rapamycin involves a previously undescribed family of enzymes acting on chorismate.Andexer JN, Kendrew SG, Nur-e-Alam M, Lazos O, Foster TA, Zimmermann AS, Warneck TD, Suthar D, Coates NJ, Koehn FE, Skotnicki JS, Carter GT, Gregory MA, Martin CJ, Moss SJ, Leadlay PF, Wilkinson B2011 Mar 2221383123