Enzyme

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EC Tree
     4. Lyases
        4.2 Carbon-oxygen lyases
            4.2.1 Hydro-lyases
ID:4.2.1.111
Description:1,5-anhydro-D-fructose dehydratase.
Alternative Name: AFDH.
AF dehydratase.
1,5-anhydro-D-fructose hydrolyase.
1,5-anhydro-D-fructose 4-dehydratase.
1,5-anhydro-D-arabino-hex-2-ulose dehydratase.
Cath: 2.60.120.990; 2.60.40.1180; 2.60.40.1760; 2.80.10.50;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 4.2.1.111
BRENDA Enzyme Link: BRENDA 4.2.1.111
KEGG Enzyme Link: KEGG4.2.1.111
BioCyc Enzyme Link: BioCyc 4.2.1.111
ExPASy Enzyme Link: ExPASy4.2.1.111
EC2PDB Enzyme Link: EC2PDB 4.2.1.111
ExplorEnz Enzyme Link: ExplorEnz 4.2.1.111
PRIAM enzyme-specific profiles Link: PRIAM 4.2.1.111
IntEnz Enzyme Link: IntEnz 4.2.1.111
MEDLINE Enzyme Link: MEDLINE 4.2.1.111
MSA:

4.2.1.111;

Phylogenetic Tree:

4.2.1.111;

Uniprot:
M-CSA:
RHEA:15725 1,5-anhydro-D-fructose = ascopyrone M + H2O
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[CH;+0:4](-[*:5])-[OH;+0:6]>>[*:1]-[C;H0;+0:2](-[*:3])=[CH;+0:4]-[*:5].[OH2;+0:6]
Reaction
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References

TitleAuthorsDatePubMed ID
The anhydrofructose pathway and its possible role in stress response and signaling.Yu S, Fiskesund R2006 Sep16822618
Enzymatic description of the anhydrofructose pathway of glycogen degradation II. Gene identification and characterization of the reactions catalyzed by aldos-2-ulose dehydratase that converts 1,5-anhydro-D-fructose to microthecin with ascopyrone M as the intermediate.Yu S2005 May 2515716041
Enzymatic description of the anhydrofructose pathway of glycogen degradation; I. Identification and purification of anhydrofructose dehydratase, ascopyrone tautomerase and alpha-1,4-glucan lyase in the fungus Anthracobia melaloma.Yu S, Refdahl C, Lundt I2004 May 315110094